Ubiquitin chain elongation: an intriguing strategy (original) (raw)

Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly

Grace Royappa

Molecular Cell, 2014

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Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C

David Yanishevski

Cell, 2016

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The APC11 RING-H2 Finger Mediates E2-Dependent Ubiquitination

Tony Hunter

Molecular Biology of the Cell, 2000

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Molecular Insights into Polyubiquitin Chain Assembly

Andrew Vandemark

Cell, 2001

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RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex

Masaya Yamaguchi, Patrick Rodrigues, Edmond Watson

Proceedings of the National Academy of Sciences of the United States of America, 2015

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A Mechanism for Protein Monoubiquitination Dependent on a trans-Acting Ubiquitin-binding Domain

Sebastien Leon

Journal of Biological Chemistry, 2013

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A ubiquitin ligase complex assembles linear polyubiquitin chains

Kazuhiro Iwai

The EMBO Journal, 2006

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Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology

Mark Peggie

Biochemical Journal, 2008

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Ubiquitin pathway: Another link in the polyubiquitin chain?

Wolfgang Dubiel

Current Biology, 1999

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UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit

Colin Godwin

Nature Cell Biology, 2009

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Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

Simona Polo

EMBO reports, 2011

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Mechanism of Polyubiquitin Chain Recognition by the Human Ubiquitin Conjugating Enzyme Ube2g2

Aroop Sircar, J. Tolman

Journal of Biological Chemistry, 2011

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A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to

Stuart Tugendreich

1995

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The ASCC2 CUE domain contacts adjacent ubiquitins to recognize K63-linked polyubiquitin

Shaheer Syed

2021

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Emerging functions of branched ubiquitin chains

Tony Hunter

Cell Discovery, 2021

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Structural Analysis of the Anaphase-Promoting Complex Reveals Multiple Active Sites and Insights into Polyubiquitylation

Wah Chiu

Molecular Cell, 2005

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APC/C-mediated multiple monoubiquitylation provides an alternative degradation signal for cyclin B1

Nevena Dimova

Nature Cell Biology, 2012

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FBG1 is a promiscuous ubiquitin ligase that sequesters APC2 and causes S-phase arrest

Ernesto Fuentes

Cell Cycle, 2010

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Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

Vishva Dixit

Nature Reviews Molecular Cell Biology, 2011

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A Novel Ubiquitination Factor, E4, Is Involved in Multiubiquitin Chain Assembly

Thorsten Hoppe

Cell, 1999

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Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins

Emma Dixon

Structure, 2016

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A 20s complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B

Stuart Tugendreich

Cell, 1995

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Generation and physiological roles of linear ubiquitin chains

Kazuhiro Iwai

BMC Biology, 2012

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A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination

David Hoyt

Molecular Cell, 2006

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Ubiquitin chain conformation regulates recognition and activity of interacting proteins

Y Ye

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Post-translational regulation of ubiquitin signaling

Zhao-Qing Luo

Journal of Cell Biology, 2019

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Faculty of 1000 evaluation for Building ubiquitin chains: E2 enzymes at work

Keith Wilkinson

F1000 - Post-publication peer review of the biomedical literature, 2011

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APC2 Cullin Protein and APC11 RING Protein Comprise the Minimal Ubiquitin Ligase Module of the Anaphase-promoting Complex

Johann Deisenhofer

Molecular Biology of the Cell, 2001

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Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles

Yelena Kravtsova-ivantsiv

Proceedings of the National Academy of Sciences of the United States of America, 2019

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An E2 Accessory Domain Increases Affinity for the Anaphase-promoting Complex and Ensures E2 Competition

Juliet Girard

Journal of Biological Chemistry, 2015

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The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines

Arie Admon

Journal of Biological Chemistry, 2010

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The ubiquitin signal: assembly, recognition and termination

Keith Wilkinson

EMBO reports, 2005

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Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases

Johann Deisenhofer

Proceedings of the National Academy of Sciences, 2005

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Mechanism of ubiquitin chain synthesis employed by a HECT domain ubiquitin ligase

Tony Hunter

Journal of Biological Chemistry, 2017

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E3Independent Monoubiquitination of Ubiquitin-Binding Proteins

Sebastian Wagner

Molecular Cell, 2007

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