PHARMACOLOGICAL ACTIVITY OF MANGROVE MEDICINAL PLANTS AGAINST PATHOGENIC BACTERIA AND FUNGI (original) (raw)
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Antimicrobial activity of mangrove plants of Goa, India against human pathogenic bacteria
2016
Mangroves grow in saline coastal habitats in the tropical and subtropical regions. Mangrove ecosystem is of a great ecological and socioeconomic significance. Mandovi-Zuari estuarine complex in Goa are well known mangrove forests on the west coast of India. Different species of mangrove plants are found and are abundant along the Mandovi estuary of Goa. Mangrove plants are explored from ancient times as folklore medicine against different bacterial and fungal infections. In this study, three different species of mangrove plants, Acanthus illicifolius, Ceriops tagal and Sonneretia caseolaris were collected from three different stations along the Mandovi estuary at Divar, Ribandar and Old Goa. The solvent extracts of dried and powdered leaves of these mangrove plants were further investigated to evaluate the antimicrobial activity against human pathogenic bacteria, Staphylococcus aureus, E.coli, Kliebsiella pneumoniae and Bacillus subtilis using well diffusion method. The results suggest an idea for further characterization of active compound from the effective mangrove plant, which can be used to control the drug resistant pathogenic bacteria.
BIOAKTIVITAS ANTIBAKTERI DARI EKSTRAK DAUN MANGROVE Avicennia sp
Jurnal Kelautan: Indonesian Journal of Marine Science and Technology
Mangrove Avicennia sp. an important mangrove species, because it used as traditional medicine. This research aimed to obtain a fraction of mangrove leaves extract Avicennia sp. which has antibacterial bioactivity against S. aureus and E. coli. Mangrove leaves collected from the coast in the village of Kabonga Besar, Donggala District, Central Sulawesi. Antibacterial activity assayed using the agar diffusion well method. The results showed the presence of steroid, triterpenoids, flavonoids, alkaloids and polyphenols compounds. Antibacterial activity showed by ethyl acetate fraction (S. aureus 16.97 ± 1.15 mm and E. coli 14.40 ± 0.46 mm) and ethanol (S. aureus 12.20 ± 2.12 mm and E. coli 8.13 ± 0.42 mm) at 1,000 mg/mL. This study has explored the antibacterial ability of Avicennia sp. leaves extract in n-hexane, ethyl acetate, and ethanol. Phytochemical analysis of various solvent extracts shows that flavonoids and tannins are common in all plant extracts with antibacterial properties. Avicennia sp. leaves extract can be used to find new bioactive natural products and can use as a potential source that can control pathogenic bacteria.
SCREENING THE INDIAN SUNDARBAN MANGROVE FOR ANTIMICROBIAL ACTIVITY
This paper examines the antimicrobial activity of aqueous extract of leaves of four mangrove plants from the Indian Sundarbans against bacteria pathogenic to humans and plant. Fresh leaves collected were surface sterilized, dried till crisp and then ground till powder and extracted with sterile distilled water for 18 hours at 70°C. The antimicrobial activity of the aqueous extract was tested using agar well diffusion technique. The length of inhibition zone was measured in millimeters. The zone of inhibition against the test pathogenic bacteria ranged from (13mm to 20mm). All the aqueous extract showed antimicrobial activity. Aqueous extract of the tested mangrove plants exhibited promising antibacterial activity. Aegialitis rotundifolia could be used in the treatment of E. coli, B. cereus and S.typhi infection. Avicennia alba and Brugeria gymnorrhiza could be used for treating Staphylococcus aureus infection. Moreover due to location of mangrove in the saline estuarine region, they are rich in photochemical which may be the reason for their antibacterial activity. Further studies are being carried out in order to isolate the compound responsible for antibacterial property.
Antibacterial activity of mangrove leaf extracts against human pathogens
Indian Journal of Pharmaceutical Sciences, 2012
Sahoo, et al.: Antibacterial Activity of Mangrove Leaves The antibacterial activity of leaf extract of mangroves, namely, Rhizophora mucronata, Sonneratia alba and Exoecaria agallocha from Chorao island, Goa was investigated against human bacterial pathogens Staphylococcus aureus, Streptococcus sp., Salmonella typhi, Proteus vulgaris and Proteus mirabilis. As compared to aqueous, ethanol extract showed broad-spectrum activity. The multidrug-resistant (MDR) bacteria Salmonella typhi was inhibited by the ethanol extract of S. alba leaf whereas the other two resistant bacteria Staphylococcus aureus and Streptococcus sp. were inhibited by the ethanol extract of leaves of all the species. The aqueous extract of S. alba and E. agallocha showed their activity against P. vulgaris and P. mirabilis, respectively. Phytochemical analysis revealed the presence of saponins, glycosides, tannins, flavonoids, phenol and volatile oils in the leaves of mangroves. Further studies using different solvents for extraction are necessary to confirm that mangroves are a better source for the development of novel antibiotics.
Phytochemical Screening and Antibacterial Activity of the Selected Species of Mangroves
JPAIR Multidisciplinary Research
As a productive ecosystem component, mangroves provide critical services to humankind. Mangroves may be a source of antibacterial compounds that could be used as a natural treatment for managing bacterial infections. This study determined the phytochemical constituents of leaf extracts of three selected mangrove species Avicennia marina (Bungalon), Rhizophora apiculata (Bakhaw), and Sonneratia alba (Pagatpat), using the Test-tube Method and antibacterial sensitivity using an Agar Well-Diffusion Method found in the coastal areas of Talisay City, Negros Occidental, Philippines. The results showed that the three species of mangroves leaf methanolic extracts exhibit susceptibility to antibacterial properties against S. aureus; it was observed that S. alba has the highest inhibitory effect on S. aureus among the three selected mangrove species. There was a significant difference between the positive control (Linezolid 30 mcg) and the methanolic crude extract of R. apiculata (MD = 27.97, ...
Mangrove plants species from Delta Mahakam, Indonesia with antimicrobial potency
Biodiversitas Journal of Biological Diversity
This research was aimed to study biodiversity of mangrove that have potential as an antimicrobial material. The leaves of 4 types of mangroves, namely Avicennia marina, Sonneratia alba, Rhizophora stylosa, and Acanthus ilicifolius were chopped, dried and extracted with 3 types of solvents 80% ethanol, water and seawater. The Antimicrobial used Agar Disc Diffusion (ADD) method, and Minimal Inhibitory Concentration (MIC). Microbes that used for the test were
Mangrove Medicinal Plants: A Review
India has a rich heritage of knowledge on plant based drugs both for use in preventive and curative medicine. A country like India is very much suited for development of drugs from medicinal plants. A large number of these plants grow wild and exploited especially for use in indigenous pharmaceutical houses. Some of these plants produce valuable drugs which have high export potential. The use of plants and plant products as medicines could be traced as far back as the beginning of human civilization. Mangrove plants have been used in folklore medicines and extracts from mangrove species have proven inhibitory activity against human, animal and plant pathogens. The present review deals with the pharmacological activity of mangrove medicinal plants. Several species of mangrove produce bioactive compounds that may control microbial growth. Also, preliminary studies have demonstrated that the mangrove plant extracts have antibacterial activity against pathogenic bacterial strains. Mangrove extracts can also be the possible sources of mosquito larvicides, antifungal, antiviral, anti-cancer and anti-diabetic compounds.
Journal of Tropical Life Science, 2020
Humans are at a continuous battle against different types of diseases, so that extraordinary effort to accelerate drug discovery has become a necessity. Indonesian biodiversity is abundant natural resources that can be utilized as potential drug sources. Mangroves are among potential plant medicines that grow nearly at all Indonesian coastlines. The aim of this study was to evaluate the potential of mangrove extracts (extract library) as antibacterial agents. In this study, eight mangroves species with 16 samples from different parts of the plants such as leaf, bark or root were collected. Four types of solvents with different polarity, namely water, ethanol, ethyl acetate and hexane were used in maceration of samples producing 64 extracts. Disk diffusion method was used for antibacterial screening using five bacterial strains. There were 37 extracts showed antibacterial potential with the lowest and the highest inhibition indexes were 0.0283 and 1.8983, respectively. The highest inhibition index was recorded for ethyl acetate extract of Bruguiera gymnorrhiza root (BgR (Ea)) against Escherichia coli. The second highest inhibition index was 0.7867 recorded water extract of Avicennia marina leaf (AmL (A)) against Staphylococcus aureus. Almost all of extract showed saponin and tannin in considerable amount. This supported the data that mangrove extracts were potential as antibacterial agents.