Novel 18F-labelled triazine derivatives for PET imaging of phosphodiesterase 2A (original) (raw)

Synthesis, 18F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography

Susann Schröder, Rodrigo Teodoro

Molecules, 2015

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Development of a fluorine-18-labeled benzoimidazotriazine-based radioligand for the imaging of phosphodiesterase 2A in the brain with positron emission tomography

RIEN RITAWIDYA

2020

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Preclinical Evaluation of 18F-PF-05270430, a Novel PET Radioligand for the Phosphodiesterase 2A Enzyme

Nabeel Nabulsi

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016

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Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission Tomography

RIEN RITAWIDYA

Molecules

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Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[e]imidazo[2,1-c][1,2,4]triazines as Phosphodiesterase 2A Inhibitors

RIEN RITAWIDYA

Molecules

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{"__content__"=>"Investigation of anF-labelled Imidazopyridotriazine for Molecular Imaging of Cyclic Nucleotide Phosphodiesterase 2A.", "sup"=>{"__content__"=>"18"}}

Rodrigo Carvalho Teodoro

Molecules (Basel, Switzerland), 2018

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Discovery and development of 11C-Lu AE92686 as a radioligand for PET imaging of phosphodiesterase10A in the brain

Claus Christoffersen

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014

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The Discovery of a Novel Phosphodiesterase (PDE) 4B-Preferring Radioligand for Positron Emission Tomography (PET) Imaging

Kuo-Hsien Fan

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Discovery and Development of 11C-Lu AE92686 as a Radioligand for PET Imaging of Phosphodiesterase10A in the Brain

Stine Ottesen

The Journal of Nuclear Medicine, 2014

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Carbon-11 and Fluorine-18 Radiolabeled Pyridopyrazinone Derivatives for Positron Emission Tomography (PET) Imaging of Phosphodiesterase-5 (PDE5)

Rufael Chekol

Journal of medicinal chemistry, 2016

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Synthesis of fluorine-containing phosphodiesterase 10A (PDE10A) inhibitors and the in vivo evaluation of F-18 labeled PDE10A PET tracers in rodent and nonhuman primate

jinda fan

Journal of medicinal chemistry, 2015

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Development of a New Radiofluorinated Quinoline Analog for PET Imaging of Phosphodiesterase 5 (PDE5) in Brain

Rodrigo Carvalho Teodoro

Pharmaceuticals (Basel, Switzerland), 2016

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First-in-Human Evaluation of18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

Sangram Nag

Journal of Nuclear Medicine

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Fluorine-Containing 6,7-Dialkoxybiaryl-Based Inhibitors for Phosphodiesterase 10 A: Synthesis and in vitro Evaluation of Inhibitory Potency, Selectivity, and Metabolism

Lenka Kubicova, Karen Nieber

ChemMedChem, 2014

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Development of Radiolabeled PET Tracers for In Vivo Visualization of Phosphodiesterase Type 5 (PDE5)

Rufael Chekol

2014

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Synthesis and initial PET imaging of new potential dopamine D3 receptor radioligands (E)-4,3,2-[11C]methoxy-N-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl-cinnamoylamides

Bruce Mock

Bioorganic & Medicinal Chemistry, 2005

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Phosphodiesterase 10A PET Radioligand Development Program: From Pig to Human

Nabeel Nabulsi

Journal of Nuclear Medicine, 2014

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Pyrido[4,3- e ][1,2,4]triazolo[4,3- a ]pyrazines as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors

PETER JOHANNES

ACS Medicinal Chemistry Letters, 2015

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Synthesis, in vitro and in vivo evaluation of [O-methyl-11C] 2-{4-[4-(3-methoxyphenyl)piperazin-1-yl]-butyl}-4-methyl-2H-[1,2,4]-triazine-3,5-dione: A novel agonist 5-HT1A receptor PET ligand

Hadassah Tamir

Bioorganic & Medicinal Chemistry Letters, 2006

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Development of [ 18 F]-Labeled Pyrazolo[4,3- e ]-1,2,4- triazolo[1,5- c ]pyrimidine (SCH442416) Analogs for the Imaging of Cerebral Adenosine A 2A Receptors with Positron Emission Tomography

Suresh Vatakuti, Shivashankar Khanapur, Soumen Paul

Journal of Medicinal Chemistry, 2014

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A homodimeric bivalent radioligand derived from 1-(2-methoxyphenyl)piperazine with high affinity for in vivo 5-HT1A receptor imaging

Niraj Singh

MedChemComm, 2012

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Radiofluorinated histamine H3 receptor antagonist as a potential probe for in vivo PET imaging: Radiosynthesis and pharmacological evaluation

Svetlana Selivanova

Bioorganic & Medicinal Chemistry, 2012

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