Value of HDL Cholesterol, Apolipoprotein A-I, Lipoprotein A-I, and Lipoprotein A-I/A-II in Prediction of Coronary Heart Disease: The PRIME Study (original) (raw)

Coronary heart disease (CHD) remains a leading cause of premature mortality in both industrialized and developing nations. The PRIME study investigates the predictive value of HDL cholesterol, apolipoprotein A-I, lipoprotein A-I, and the ratio of lipoprotein A-I to A-II on coronary heart disease risk, emphasizing the need for prospective cohort studies to understand geographical disparities in CHD incidence. Results indicate a significant correlation between lower levels of these lipoproteins and increased CHD risk, suggesting their potential utility in risk stratification.