Nociceptor excitation by thermal sensitization--a hypothesis (original) (raw)

Thermal nociceptive properties of trigeminal afferent neurons in rats

David Yeomans

Molecular Pain, 2010

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Investigation of Thermal Hyperalgesia and Antinociceptive Effects of Drugs with Measurement of the Behavioural Noxious Heat Threshold in the Rat

Róbert Almási

2008

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Development of Thermal Nociception In Rats

Alex Stolberg, Hanan Frenk

Pain, 1996

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Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses

Martin Koltzenburg

The Journal of Neuroscience, 2004

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The ADP Receptor P2Y1 is Necessary for Normal Thermal Sensitivity In Cutaneous Polymodal Nociceptors

Derek Molliver

Molecular …, 2011

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Response of C fibre nociceptors in the anaesthetized monkey to heat stimuli: correlation with pain threshold in humans

Richard Meyer

The Journal of Physiology, 1995

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Differential modulation of thermal preference after sensitization by optogenetic or pharmacological activation of heat-sensitive nociceptors

Maham Zain

2020

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Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve

Peter Reeh

European Journal of Neuroscience, 2007

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Mechanisms of thermal sensitivity in rodent primary afferent neurons innervating the skin

Nisha Vastani

2009

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Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat

Charles Robinson

The Journal of …, 1982

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Temperature increase significantly enhances nociceptive responses of C-fibers to ATP, high K+, and acidic pH in mice

Volodymyr Khmyz

Frontiers in Cellular Neuroscience

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A novel heat-activated current in nociceptive neurons and its sensitization by bradykinin

Peter McNaughton

Proceedings of the National …, 1996

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Role for Medullary Pain Facilitating Neurons in Secondary Thermal Hyperalgesia

Miranda Neubert

Journal of Neurophysiology, 2005

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Basic Neuroscience A modified Hargreaves' method for assessing threshold temperatures for heat nociception

Shirley Saravia

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Noxious heat-induced CGRP release from rat sciatic nerve axons in vitro

Peter Reeh

European Journal of Neuroscience, 2001

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Role of Peptidergic Nerve Terminals in the Skin: Reversal of Thermal Sensation by Calcitonin Gene-Related Peptide in TRPV1-Depleted Neuropathy

Sung-tsang Hsieh

PLoS ONE, 2012

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Projected pain from noxious heat stimulation of an exposed peripheral nerve - A case report

Peter Reeh

European Journal of Pain, 2009

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Inflammatory Pain: The Cellular Basis of Heat Hyperalgesia

Jiehong Huang, Peter McNaughton

Current Neuropharmacology, 2006

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Responses to heat of C-fiber nociceptors in monkey are altered by injury in the receptive field but not by adjacent injury

Srinivasa Raja

Pain, 1988

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Effects of Thermo-sensitive Transient Receptor Potential (TRP) Channel Agonists on the Neural Coding of Touch, Temperature and Pain Sensation

Merab Tsagareli, Earl Carstens, Gulnazi Gurtskaia

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Inactivation and tachyphylaxis of heat-evoked inward currents in nociceptive primary sensory neurones of rats

Dietrich Büsselberg

The Journal of Physiology, 2000

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Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene

Katharina Zimmermann

Proceedings of the National Academy of Sciences, 2005

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Noxious, but not innocuous, thermal stimuli evoke pERK expression in dorsal horn neurons after spared nerve injury in adult rats

Sumaiya Shaikh

Neuroscience letters, 2017

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Prostaglandin E2 and I2 facilitate noxious heat-induced spike discharge but not iCGRP release from rat cutaneous nociceptors

Gábor Pethô

Life Sciences, 2007

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Stimulation of PAR-2 excites and sensitizes rat cutaneous C-nociceptors to heat

Martin Michaelis, Beate Averbeck

Neuroreport, 2004

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Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers

Michael Jankowski, Jeffrey Lawson

Molecular Pain, 2010

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A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Jean Joris

Pain, 1988

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Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat

Lorne Mendell

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Behavioral Testing of the Effects of Thermosensitive TRP Channel Agonists on Touch, Temperature, and Pain Sensations

Merab Tsagareli

Neurophysiology, 2011

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Peripheral voltage-gated calcium channels in skin are essential for transient neurogenic thermal hyperalgesia in mice

Eduardo lopez soto

2020

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Differential contribution of TRPV1 to thermal responses and tissue injury-induced sensitization of dorsal horn neurons in laminae I and V in the mouse

William Eckert

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