Human Melatonin Regulation is Hut Mediated by the Three Cone Photopii: Visual System (original) (raw)

Journal of Clinical …, 2001

Abstract

The aim of this study was to test if the three cone photopic visual system is the primary ocular photoreceptor input for human circadian regulation by determining the effects of different wavelengths on light-induced melatonin suppression. Healthy subjects with stable sleeping patterns (wake-up time 7: 30 AM i 12 min) and normal color vision were exposed at night to full-���eld 505 nm or 555 nm monochromatic stimuli or darkness for 90 min. Plasma collected before and after exposures was quantified for melatonin. Subjects ...

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