The lipid theory in the pathogenesis of calcific aortic stenosis (original) (raw)

Mechanisms of aortic valve calcification: the LDL-density-radius theory: a translation from cell signaling to physiology

Nalini Rajamannan

American Journal of Physiology-heart and Circulatory Physiology, 2010

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A Not-So-Little Role for Lipoprotein(a) in the Development of Calcific Aortic Valve Disease

Elena Aikawa

Circulation, 2015

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High-density lipoproteins (HDL) are present in stenotic aortic valves and may interfere with the mechanisms of valvular calcification

Miriam Lee-Rueckert, Jaakko Lommi

Atherosclerosis, 2011

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Atherosclerotic inflammation triggers osteogenic bone transformation in calcified and stenotic human aortic valves: Still a matter of debate

Christoph Garlichs

Experimental and Molecular Pathology, 2009

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The role of inflammation and metabolic risk factors in the pathogenesis of calcific aortic valve stenosis

Emilio Attena

Aging Clinical and Experimental Research

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Osteoprotegerin Inhibits Aortic Valve Calcification and Preserves Valve Function in Hypercholesterolemic Mice

M. Bridget Zimmerman

PLoS ONE, 2013

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Aortic stenosis, atherosclerosis, and skeletal bone: is there a common link with calcification and inflammation?

Phoebe Makiello

European Heart Journal, 2013

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Human Degenerative Valve Disease Is Associated With Up-Regulation of Low-Density Lipoprotein Receptor-Related Protein 5 Receptor-Mediated Bone Formation

Thomas Spelsberg

Journal of the American College of Cardiology, 2006

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Atorvastatin Inhibits Hypercholesterolemia-Induced Cellular Proliferation and Bone Matrix Production in the Rabbit Aortic Valve

ravinder singh

2000

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High-Density Lipoprotein Regulates Calcification of Vascular Cells

Yin Tintut

Circulation Research, 2002

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Lipid-Lowering Therapy in Calcific Aortic Stenosis

Kwan Chan

New England Journal of Medicine, 2005

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Pathological significance of lipoprotein(a) in aortic valve stenosis

Kashif Khan

Atherosclerosis, 2018

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Lipoprotein(a)-Associated Molecules Are Prominent Components in Plasma and Valve Leaflets in Calcific Aortic Valve Stenosis

Andrea Edel

JACC: Basic to Translational Science, 2017

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Lipoprotein(a) and Calcific Aortic Valve Stenosis

Peter D. Montan Y.

European medical journal, 2019

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Pathophysiologic mechanisms of calcific aortic stenosis

Andreas Kaoukis

Therapeutic advances in cardiovascular disease, 2012

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Lipoprotein Particle Profiles Compared With Standard Lipids in the Association With Subclinical Aortic Valve Calcification in Apparently Healthy Japanese Men

Thien Vu

Circulation Journal, 2021

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The Roles of Lipid Oxidation Products and Receptor Activator of Nuclear Factor- B Signaling in Atherosclerotic Calcification

Yin Tintut

Circulation Research, 2011

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Endoplasmic Reticulum Stress Participates in Aortic Valve Calcification in Hypercholesterolemic Animals

Baohui Yang

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013

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The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography

Zuhier Awan, Maxime Denis

Atherosclerosis, 2011

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Valvular osteoclasts in calcification and aortic valve stenosis severity

Mohamed Yousry

2013

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Aortic valve calcification: association with bone mineral density and cardiovascular risk factors

Hasan Turhan

Coronary Artery Disease, 2005

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Calcific aortic stenosis: another face of atherosclerosis?

G. Novaro

European Journal of Cardiovascular Prevention & Rehabilitation, 2006

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Advances in Pathophysiology of Calcific Aortic Valve Disease Propose Novel Molecular Therapeutic Targets

Cécile Oury

Frontiers in Cardiovascular Medicine

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Noncollagenous bone matrix proteins as a part of calcific aortic valve disease regulation

Tatu Juvonen

Human Pathology, 2008

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Interaction of Age With Lipoproteins as Predictors of Aortic Valve Calcification in the Multi-Ethnic Study of Atherosclerosis

Jeffrey Probstfield

Archives of Internal Medicine, 2008

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Correlation between plasma osteopontin levels and aortic valve calcification: Potential insights into the pathogenesis of aortic valve calcification and stenosis

Paolo Mignatti

The Journal of Thoracic and Cardiovascular Surgery, 2009

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A comprehensive study of calcific aortic stenosis: from rabbit to human samples

Luis Padial

Disease models & mechanisms, 2018

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Measures of high-density lipoprotein function in men and women with severe aortic stenosis

Anouar Hafiane

Lipids in Health and Disease, 2022

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