The hidden face of food phenolic composition (original) (raw)
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Polyphenols: From Theory to Practice
2021
Background: The importance of polyphenols in human health is well known; these compounds are common in foods, such as fruits, vegetables, spices, extra virgin olive oil and wine. On the other hand, the different factors that modulate the biological activity of these compounds are less well known. Conceptualization of the work: In this review we took into account about 200 relevant and recent papers on the following topics: "polyphenols bioavailability", "polyphenols matrix effect", "food matrix effect", "polyphenols-cytochromes interaction", after having reviewed and updated information on chemical classification and main biological properties of polyphenols, such as the antioxidant, anti-radical and anti-inflammatory activity, together with the tricky link between in vitro tests and clinical trials. Key findings: the issue of polyphenols bioavailability and matrix effect should be better taken into account when health claims are referred to polyphenols, thus considering the matrix effect, enzymatic interactions, reactions with other foods or genetic or gender characteristics that could interfere. We also discovered that in vitro studies often underrate the role of phytocomplexes and thus we provided practical hints to describe a clearer way to approach an investigation on polyphenols for a more resounding transfer to their use in medicine.
Polyphenols: Chemistry, Dietary Sources, Metabolism, and Nutritional Significance
Nutrition Reviews, 2009
constitute one of the most numerous and ubiquitous groups of plant metabolites and are an integral pat? of both human and animal diets. Ranging from simple phenolic molecules to highly polymerized compounds with molecular weights of greater than 30,000 Da, the occurrence of this complex group of substances in plant foods is extremely variable. Polyphenols traditionally have been considered antinutrients by animal nutruonists, because of the adverse effect of tannins, one type of polyphenol, on protein digestibility. However, recent interest in food phenolics has increased greatly, owing to their antioxidant capacity (free radical scavenging and metal chelating activities) and their possible beneficial implications in human health, such as in the treatment and prevention of cancer, cardiovascular disease, and other pathologies. Much of the literature refers to a single group of plant phenolics, the flavonoids. This review offers an overview of the nutritional effects of the main groups of polyphenolic compounds, including their metabolism, effects on nutrient bioavailabilityl and antioxidant activityl as well as a brief description of the chemistry of polyphenols and their occurrence in plant foods.
Polyphenols: food sources and bioavailability 1,2
Polyphenols are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases such as cancer and cardiovascular diseases is emerging. The health effects of polyphenols depend on the amount consumed and on their bioavailability. In this article, the nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed. Estimates of dietary intakes are given for each class of polyphenols. The bioavailability of polyphenols is also reviewed, with particular focus on intestinal absorption and the influence of chemical structure (eg, glycosylation, esterification, and polymerization), food matrix, and excretion back into the intestinal lumen. Information on the role of microflora in the catabolism of polyphenols and the production of some active metabolites is presented. Mechanisms of intestinal and hepatic conjugation (methylation, glucuronidation, sulfation), plasma transport, and elimination in bile and urine are also described. Pharmacokinetic data for the various polyphenols are compared. Studies on the identification of circulating metabolites, cellular uptake, intracellular metabolism with possible deconjugation, biological properties of the conjugated metabolites, and specific accumulation in some target tissues are discussed. Finally, bioavailability appears to differ greatly between the various polyphenols, and the most abundant polyphenols in our diet are not necessarily those that have the best bioavailability profile. A thorough knowledge of the bioavailability of the hundreds of dietary polyphenols will help us to identify those that are most likely to exert protective health effects.
Polyphenols: food sources and bioavailability
The American journal of clinical nutrition, 2004
Polyphenols are abundant micronutrients in our diet, and evidence for their role in the prevention of degenerative diseases such as cancer and cardiovascular diseases is emerging. The health effects of polyphenols depend on the amount consumed and on their bioavailability. In this article, the nature and contents of the various polyphenols present in food sources and the influence of agricultural practices and industrial processes are reviewed. Estimates of dietary intakes are given for each class of polyphenols. The bioavailability of polyphenols is also reviewed, with particular focus on intestinal absorption and the influence of chemical structure (eg, glycosylation, esterification, and polymerization), food matrix, and excretion back into the intestinal lumen. Information on the role of microflora in the catabolism of polyphenols and the production of some active metabolites is presented. Mechanisms of intestinal and hepatic conjugation (methylation, glucuronidation, sulfation),...
Human intervention trials have provided evidence for protective effects of various (poly)phenol-rich foods against chronic disease, including cardiovascular disease, neurodegeneration, and cancer. While there are considerable data suggesting benefits of (poly)phenol intake, conclusions regarding their preventive potential remain unresolved due to several limitations in existing studies. Bioactivity investigations using cell lines have made an extensive use of both (poly)phenolic aglycones and sugar conjugates, these being the typical forms that exist in planta, at concentrations in the low-lM-to-mM range. However, after ingestion, dietary (poly)phenolics appear in the circulatory system not as the parent compounds, but as phase II metabolites, and their presence in plasma after dietary intake rarely exceeds nM concentrations. Substantial quantities of both the parent compounds and their metabolites pass to the colon where they are degraded by the action of the local microbiota, giving rise principally to small phenolic acid and aromatic catabolites that are absorbed into the circulatory system. This comprehensive review describes the different groups of compounds that have been reported to be involved in human nutrition, their fate in the body as they pass through the gastrointestinal tract and are absorbed into the circulatory system, the evidence of their impact on human chronic diseases, and the possible mechanisms of action through which (poly)phenol metabolites and catabolites may exert these protective actions. It is concluded that better performed in vivo intervention and in vitro mechanistic studies are needed to fully understand how these molecules interact with human physiological and pathological processes. Antioxid. Redox Signal. 18, 1818-1892.
Polyphenols: Properties, Occurrence, Content in Food and Potential Effects
Recently, polyphenol compounds occupy a unique place in environmental science as important class of bioactive natural products worldwide. The most abundant polyphenols are the condensed tannins. Polyphenols found almost in all families of plants and are concentrated in leaf tissue, the epidermis, bark layers, flowers and fruits. The biological properties of polyphenols include anticancer, antioxidant and anti-inflammatory effects. Polyphenols posses anti-microbial and anti-cariogenic properties and is an important source as anti-infective agents against antibiotic-resistant human pathogens. As antioxidants, polyphenols are the most abundant in Man diet. Dietary intake requirement is 1 g/d that can be achieved by consuming a wide array of plant foods. Cereals, vegetables, dry legumes and chocolate contribute to the intake of polyphenols. Olive mill wastewater (OMW) contains phenolic compounds. Their recovery is an advantage for several industrial sectors, including medicine, cosmetic, and food preservation. Therefore, OMW could represent an important alternative source of biologically active polyphenols.
The American Journal of Clinical Nutrition, 2005
Bitterness and astringency are found in a variety of foods, including nuts, fruits, chocolate, tea, wine, and soymilk. In fruits and beverages, the taste of bitterness and the tactile sensation of astringency are elicited primarily by flavanol polymers (proanthocyanidins or condensed tannins). Variations in proanthocyanidin composition, such as polymer size, extent of galloylation, and formation of derivatives, affect both bitterness and astringency. In beverages, other factors also influence these sensations, including the pH and the levels of ethanol, sweetness, and viscosity. Similarly, foods eaten with beverages can influence astringency. For example, eating dark chocolate increases the astringency of red wine more than does milk chocolate. Individuals perceive astringency differently because of variations in salivary flow rates, and preferences for and acceptance of a product may vary tremendously among individuals; decreasing bitterness and/or astringency may not increase preference. Factors influencing bitterness, astringency, and individual preference decisions are discussed.
The Influence and the Role of Polyphenols on the Sensory and Organoleptic Aspects of Food
2015
A vast majority of food products found on the market contains specific, potentially toxic substances, whether those substances appeared as a result of food contamination by an exterior factor or during the production. As an examples of food contamination we can consider bacterial and fungal toxins, where the latter (mycotoxins) include some evidently mutagenic or genotoxic compounds, i.e. potentially cancerogenic compounds. Mycotoxins may enter the food chain via direct or indirect contamination. In direct contamination, the food products represent the basis for the development of toxigenic moulds (almoust all food products may represent a basis for the mould development during their production, processing and storage). Bioactive plant polyphenols are relatively well-known for their antioxidant, anti-mutagenic, anticancerogenous, anti-inflamatory, antiangiogenic, antiulcer and antimicrobial characteristics. Many plant ingredients and extracts are reported to prevent the mould develo...
Variation in polyphenol content due to commonly applied processing techniques: A review
2018
The present review is all about the effects of various commonly used processing methods in our country and is based upon the evaluation of previous studies depicting various food processing applications with its effects on raw ingredient. This review deals with various subclasses of phenolic compounds as phenolic acids, chalcones, flavanones, flavones, flavonols and tannins, and the changes these compounds undergo during processing. Health properties of poly-phenolic compounds are also discussed to emphasize their importance as integral part of our diet. After going through several researches it was found that the effect of same processing method can be different for different subclasses of polyphenols and the effect can also vary according to variety of the raw ingredient. Most of the processing techniques such as blanching, boiling, microwaving etc. tend to degrade the quantity of polyphenols present in raw form but it was also seen that sometimes it increases the bioavailability ...