Activation and repression of a b-globin gene in cell hybrids is accompanied by a shift in its temporal regulation (original) (raw)
The coordinate replication of the human β-globin gene domain reflects its transcriptional activity and nuclease hypersensitivity
Carl Schildkraut
Molecular and Cellular Biology
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Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids
Thalia Papayannopoulou
Nucleic Acids Research, 1987
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Replication of alpha and beta globin DNA sequences occurs during early S phase in murine erythroleukemia cells
Elliot Epner
Proceedings of the National Academy of Sciences, 1981
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Extinction of globin gene expression in human fibroblast � mouse erythroleukemia cell hybrids
ramon velez
Somatic Cell Genetics, 1976
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Distribution of the globin gene in active and inactive chromatin fractions from friend erythroleukemia cells
Anthony Faras
Experimental Cell Research, 1978
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The Locus Control Region Is Necessary for Gene Expression in the Human b-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid Cells
Andreas Reik, Elliot Epner
1998
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The Locus Control Region Is Necessary for Gene Expression in the Human β-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid Cells
Andreas Reik
Molecular and Cellular Biology, 1998
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A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus
W. Forrester, Elliot Epner
Genes & Development, 1990
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Intergenic Transcription and Developmental Remodeling of Chromatin Subdomains in the Human β-globin Locus
Karin Diderich
Molecular Cell, 2000
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Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny
Thalia Papayannopoulou
Experimental Hematology, 2013
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Coactivation of human α1- and α2-globin genes in single induced MEL cells containing one human α-globin locus
Francois Morle
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1997
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Asynchronous DNA replication within the human beta-globin gene locus
W. Forrester, Elliot Epner
Proceedings of the National Academy of Sciences, 1988
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Adult and fetal human globin genes are expressed following chromosomal transfer into MEL cells
V. Najfeld
Proceedings of the National Academy of Sciences, 1985
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DNA sequences required for regulated expression of β-globin genes in murine erythroleukemia cells
A. Athanassiadou
Cell, 1984
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Comparative analysis of the locus control region of the rabbit β-like globin gene cluster: HS3 increases transient expression of an embryonic ε-globin gene
Olga Selifonova
Nucleic Acids Research, 1993
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Globin Gene Switching
Thalia Papayannopoulou
Journal of Biological Chemistry, 1996
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Long-Distance Control of Origin Choice and Replication Timing in the Human beta -Globin Locus Are Independent of the Locus Control Region
Andreas Reik, Elliot Epner
Molecular and Cellular Biology, 2000
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The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells
Andreas Reik
Molecular and cellular biology, 1998
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The β-major and β-minor globin genes in murine erythroleukemia cells replicate during the same early interval of the S phase
Carl Schildkraut
Biochemical and Biophysical Research Communications, 1984
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Localization of the human α-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay
Raju Kucherlapati
Cell, 1977
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The Dynamics of Globin Gene Expression and Gene Therapy Vectors
Niall Dillon
Annals of The New York Academy of Sciences, 1998
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Chromosomal localization of human globin gene on human chromosome 11 in somatic cell hybrids
Jeanne B Lawrence
Proceedings of the National Academy of Sciences, 1978
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Promoters of the murine embryonic -like globin genes Ey and h1 do not compete for interaction with the -globin locus control region
Steven Fiering
Proceedings of the National Academy of Sciences, 2003
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Mechanisms of developmental control of transcription in the murine alpha - and beta -globin loci
Peter Fraser
Genes & Development, 1999
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Chromosomal localization of human β globin gene on human chromosome 11 in somatic cell hybrids
Jeanne B Lawrence
Proceedings of the …, 1978
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Replication Initiation Patterns in the -Globin Loci of Totipotent and Differentiated Murine Cells: Evidence for Multiple Initiation Regions
Geoffrey Wahl
Molecular and Cellular Biology, 2002
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Replication Initiation Patterns in the β-Globin Loci of Totipotent and Differentiated Murine Cells: Evidence for Multiple Initiation Regions
Geoff Wahl
Molecular and Cellular Biology, 2002
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2 The regulation of human globin gene expression
Niall Dillon
1993
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Negative control of hemoglobin production in somatic cell hybrids due to heme deficiency
Susan Benoff
Proceedings of the National Academy of Sciences, 1978
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Chromatin Dynamics of the mouse β-globin locus
Wiggert Van Cappellen
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Developmental regulation of fetal to adult globin gene switching in human fetal erythroid × mouse erythroleukemia cell hybrids
Thalia Papayannopoulou
Developmental Biology, 1991
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Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes
Michael Antoniou
Genes & Development, 1993
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Intergenic transcription and transinduction of the human beta -globin locus
Peter Fraser
Genes & Development, 1997
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DNA replication timing of the human β-globin domain is controlled by histone modification at the origin
Dr Amalia Tabib
Genes & Development, 2008
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Regulatory factors specific for adult and embryonic globin genes may govern their expression in erythroleukemia cells
N. Anagnou
Blood, 1985
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