Identification and partial characterization of plasma membrane polypeptides of Trypanosoma brucei (original) (raw)

This study focuses on the identification and characterization of plasma membrane polypeptides from Trypanosoma brucei, the causative agent of sleeping sickness. Using a combination of iodination, subcellular fractionation, and electrophoresis, key polypeptides associated with the parasite's variable surface coat and their distribution in various membrane fractions were analyzed. The findings contribute to understanding the structural components of the trypanosome cell surface, which plays a critical role in host-parasite interactions.