SALL1, the gene mutated in Townes-Brocks syndrome, encodes a transcriptional repressor which interacts with TRF1/PIN2 and localizes to pericentromeric heterochromatin (original) (raw)

Defining the heterochromatin localization and repression domains of SALL1

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Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2006

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Sall1, a causative gene for Townes–Brocks syndrome, enhances the canonical Wnt signaling by localizing to heterochromatin

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RLF2, a subunit of yeast chromatin assembly factor-I, is required for telomeric chromatin function in vivo

Judith Berman

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Interaction of the developmental regulator SALL1 with UBE2I and SUMO-1

Christian Netzer

Biochemical and Biophysical Research Communications, 2002

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Phosphorylation Site Mutations in Heterochromatin Protein 1 (HP1) Reduce or Eliminate Silencing Activity

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Chromatin Domain Boundaries Delimited by a Histone-binding Protein in Yeast

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A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1

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Journal of Cell Science, 2002

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Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation

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Expression of a truncated Sall1 transcriptional repressor is responsible for Townes-Brocks syndrome birth defects

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Heterochromatin Protein 2 Interacts with Nap-1 and NURF: A Link between Heterochromatin-Induced Gene Silencing and the Chromatin Remodeling Machinery in Drosophila

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The Cul4-Ddb1Cdt2 Ubiquitin Ligase Inhibits Invasion of a Boundary-Associated Antisilencing Factor into Heterochromatin

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Transcription factor CTF1 acts as a chromatin domain boundary that shields human telomeric genes from silencing

Jacques S Beckmann

Molecular and cellular biology, 2009

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Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family

José Ortiz

Embo Journal, 1999

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The molecular basis for stability of heterochromatin-mediated silencing in mammals

Sheila Xie, Ana Pombo

Epigenetics & Chromatin, 2009

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The HP1 protein family: getting a grip on chromatin

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Genome-wide control of heterochromatin replication by the telomere capping protein TRF2

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2018

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A role for heterochromatin protein 1 at human telomeres

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Chromatin modifiers and tumor suppression

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Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2001

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Purification and Characterization of a Human Factor That Assembles and Remodels Chromatin

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Journal of Biological Chemistry, 2000

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Assembling heterochromatin in the appropriate places: A boost is needed

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Journal of Cellular Physiology, 2009

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The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain

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Chromatin remodeling and transcription

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The Many Faces of Chromatin Remodeling

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Appearance and heterochromatin localization of HP1α in early mouse embryos depends on cytoplasmic clock and H3S10 phosphorylation

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The LRS and SIN domains: two structurally equivalent but functionally distinct nucleosomal surfaces required for transcriptional silencing

Craig Peterson

Molecular and cellular biology, 2006

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Drosophila Heterochromatin Protein 1 (HP1)/Origin Recognition Complex (ORC) Protein Is Associated with HP1 and ORC and Functions in Heterochromatin induced Silencing

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The Myb/SANT domain of the telomere-binding protein TRF2 alters chromatin structure

Terace Fletcher

Nucleic Acids Research, 2009

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