Impact of Oral Sildenafil on Exercise Performance in Children and Young Adults After the Fontan Operation: A Randomized, Double-Blind, Placebo-Controlled, Crossover Trial (original) (raw)

Abstract

Background-Children and young adults with single ventricle physiology have abnormal exercise capacity after Fontan operation. A medication capable of decreasing pulmonary vascular resistance should allow for improved cardiac filling and improved exercise capacity.

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