Activation of TLR9 in Dendritic Cells Recruitment and Endo-Lysosomal (original) (raw)
AI-generated Abstract
Toll-like receptor 9 (TLR9) plays a critical role in the innate immune response by recognizing immunostimulatory oligodeoxynucleotides containing unmethylated CpG motifs, particularly in the context of infections with protozoan parasites like Trypanosoma cruzi, which causes Chagas disease. This study examines the activation of TLR9 in dendritic cells and its significance in the recruitment of these cells during infections, showcasing the pathway through which TLR9 influences cytokine production and host resistance.
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