Relief as a Reward: Hedonic and Neural Responses to Safety from Pain (original) (raw)

Abstract

Relief fits the definition of a reward. Unlike other reward types the pleasantness of relief depends on the violation of a negative expectation, yet this has not been investigated using neuroimaging approaches. We hypothesized that the degree of negative expectation depends on state ( ...

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References (53)

  1. Tanimoto H, Heisenberg M, Gerber B (2004) Experimental psychology: Event timing turns punishment to reward. Nature 430: 983.
  2. Leknes S, Tracey I (2008) A common neurobiology for pain and pleasure. Nat Rev Neurosci 9: 314-320.
  3. Leknes S, Brooks JCW, Wiech K, Tracey I (2008) Pain relief as an opponent process: a psychophysical investigation. Eur J Neurosci 28: 794-801.
  4. Andreatta M, Muhlberger A, Yarali A, Gerber B, Pauli P (2010) A rift between implicit and explicit conditioned valence in human pain relief learning. Proc Biol Sci 277: 2411-2416.
  5. Smith MP, Buchanan G (1954) Acquisition of secondary reward by cues associated with shock reduction. J Exp Psychol 48: 123-126.
  6. Scott DJ, Stohler CS, Egnatuk CM, Wang H, Koeppe RA, et al. (2007) Individual differences in reward responding explain placebo-induced expecta- tions and effects. Neuron 55: 325-336.
  7. Seymour B, O'Doherty JP, Koltzenburg M, Wiech K, Frackowiak R, et al. (2005) Opponent appetitive-aversive neural processes underlie predictive learning of pain relief. Nat Neurosci 8: 1234-1240.
  8. Kim H, Shimojo S, O'Doherty JP (2006) Is avoiding an aversive outcome rewarding? Neural substrates of avoidance learning in the human brain. PLoS Biol 4: e233.
  9. Ursu S, Carter CS (2005) Outcome representations, counterfactual comparisons and the human orbitofrontal cortex: implications for neuroimaging studies of decision-making. Cognitive Brain Research 23: 51-60.
  10. Cabanac M (1979) Sensory pleasure. Q Rev Biol 54: 1-29.
  11. Berns GS, McClure SM, Pagnoni G, Montague PR (2001) Predictability modulates human brain response to reward. J Neurosci 21: 2793-2798.
  12. Schultz W (2007) Behavioral dopamine signals. Trends Neurosci 30: 203-210.
  13. Abler B, Walter H, Erk S, Kammerer H, Spitzer M (2006) Prediction error as a linear function of reward probability is coded in human nucleus accumbens. Neuroimage 31: 790-795.
  14. Bensafi M, Porter J, Pouliot S, Mainland J, Johnson B, et al. (2003) Olfactomotor activity during imagery mimics that during perception. Nat Neurosci 6: 1142-1144.
  15. Halpern AR, Zatorre RJ, M, Johnson JA (2004) Behavioral and neural correlates of perceived and imagined musical timbre. Neuropsychologia 42: 1281-1292.
  16. Jackson PL, Brunet E, Meltzoff AN, Decety J (2006) Empathy examined through the neural mechanisms involved in imagining how I feel versus how you feel pain. Neuropsychologia 44: 752-761.
  17. Brooks JCW, Zambreanu L, Godinez A, Craig AD, Tracey I (2005) Somatotopic organisation of the human insula to painful heat studied with high resolution functional imaging. NeuroImage 27: 201-209.
  18. Fairhurst M, Wiech K, Dunckley P, Tracey I (2007) Anticipatory brainstem activity predicts neural processing of pain in humans. Pain 128: 101-110.
  19. Wise RG, Rogers R, Painter D, Bantick S, Ploghaus A, et al. (2002) Combining fMRI with a pharmacokinetic model to determine which brain areas activated by painful stimulation are specifically modulated by remifentanil. Neuroimage 16: 999-1014.
  20. Snaith R, Hamilton M, Morley S, Humayan A, Hargreaves D, et al. (1995) A scale for the assessment of hedonic tone the Snaith-Hamilton Pleasure Scale. Br J Psychiatry 167: 99-103.
  21. Scheier MF, Carver CS, Bridges MW (1994) Distinguishing optimism from neuroticism (and trait anxiety, self-mastery, and self-esteem): a reevaluation of the Life Orientation Test. J Pers Soc Psychol 67: 1063-1078.
  22. Rauch WA, Schweizer K, Moosbrugger H (2007) Method effects due to social desirability as a parsimonious explanation of the deviation from unidimension- ality in LOT-R scores. Pers Individ Dif 42: 1597-1607.
  23. Jenkinson M, Smith S (2001) A Global Optimisation Method for Robust Affine Registration of Brain Images. Medical Image Analysis 5: 143-156.
  24. Smith SM (2002) Fast robust automated brain extraction. Hum Brain Mapp 17: 143-155.
  25. Woolrich MW, Ripley BD, Brady M, Smith SM (2001) Temporal autocorre- lation in univariate linear modeling of FMRI data. Neuroimage 14: 1370-1386.
  26. Jenkinson M, Bannister P, Brady M, Smith S (2002) Improved Optimisation for the Robust and Accurate Linear Registration and Motion Correction of Brain Images. NeuroImage 17: 825-841.
  27. Woolrich MW, Behrens TEJ, Beckmann CF, Jenkinson M, Smith SM (2004) Multi-level linear modelling for FMRI group analysis using Bayesian inference. Neuroimage 21: 1732-1747.
  28. Beckmann C, Jenkinson M, Smith SM (2003) General multi-level linear modelling for group analysis in FMRI. NeuroImage 20: 1052-1063.
  29. Worsley KJ (2001) Statistical analysis of Activation Images. In: Jezzard P, Matthews PM, Smith SM, eds. Functional MRI: An Introduction to Methods. Oxford: OUP. pp Ch 14.
  30. Worsley KJ, Marrett S, Neelin P, Vandal AC, Friston KJ, et al. (1996) A unified statistical approach for determining significant signals in images of cerebral activation. Human Brain Mapping 4: 58-73.
  31. Drevets WC, Gautier C, Price JC, Kupfer DJ, Kinahan PE, et al. (2001) Amphetamine-induced dopamine release in human ventral striatum correlates with euphoria. Biol Psychiatry 49: 81-96.
  32. Knutson B, Fong G, Adams C, Varner J, Hommer D (2001) Dissociation of reward anticipation and outcome with event-related fMRI. Neuroreport 12: 3683-3687.
  33. Knutson B, Fong GW, Bennett SM, Adams CM, Hommer D (2003) A region of mesial prefrontal cortex tracks monetarily rewarding outcomes: characterization with rapid event-related fMRI. NeuroImage 18: 263-272.
  34. O'Doherty J, Winston J, Critchley H, Perrett D, Burt DM, et al. (2003) Beauty in a smile: the role of medial orbitofrontal cortex in facial attractiveness. Neuropsychologia 41: 147-155.
  35. Kringelbach ML, O'Doherty J, Rolls ET, Andrews C (2003) Activation of the Human Orbitofrontal Cortex to a Liquid Food Stimulus is Correlated with its Subjective Pleasantness. Cereb Cortex 13: 1064-1071.
  36. Smith KS, Berridge KC (2007) Opioid Limbic Circuit for Reward: Interaction between Hedonic Hotspots of Nucleus Accumbens and Ventral Pallidum. J Neurosci 27: 1594-1605.
  37. Valet M, Sprenger T, Boecker H, Willoch F, Rummeny E, et al. (2004) Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain-an fMRI analysis. Pain 109: 399-408.
  38. Wagner KJ, Sprenger T, Kochs EF, Tolle TR, Valet M, et al. (2007) Imaging human cerebral pain modulation by dose-dependent opioid analgesia: a positron emission tomography activation study using remifentanil. Anesthesiology 106: 548-556.
  39. Peyron R, Faillenot I, Mertens P, Laurent B, Garcia-Larrea L (2007) Motor cortex stimulation in neuropathic pain. Correlations between analgesic effect and hemodynamic changes in the brain. A PET study. NeuroImage 34: 310-321.
  40. Baumgartner U, Buchholz HG, Bellosevich A, Magerl W, Siessmeier T, et al. (2006) High opiate receptor binding potential in the human lateral pain system. Neuroimage 30: 692-699.
  41. Bingel U, Lorenz J, Schoell E, Weiller C, Buchel C (2006) Mechanisms of placebo analgesia: rACC recruitment of a subcortical antinociceptive network. Pain 120: 8-15.
  42. Petrovic P, Kalso E, Petersson KM, Ingvar M (2002) Placebo and Opioid Analgesia-Imaging a Shared Neuronal Network. Science 295: 1737-1740.
  43. Wager TD, Rilling JK, Smith EE, Sokolik A, Casey KL, et al. (2004) Placebo- Induced Changes in fMRI in the Anticipation and Experience of Pain. Science 303: 1162-1167.
  44. Berns GS, Chappelow J, Cekic M, Zink CF, Pagnoni G, et al. (2006) Neurobiological Substrates of Dread. Science 312: 754-758.
  45. Atlas LY, Bolger N, Lindquist MA, Wager TD (2010) Brain Mediators of Predictive Cue Effects on Perceived Pain. J Neurosci 30: 12964-12977.
  46. Keltner JR, Furst A, Fan C, Redfern R, Inglis B, et al. (2006) Isolating the Modulatory Effect of Expectation on Pain Transmission: A Functional Magnetic Resonance Imaging Study. J Neurosci 26: 4437-4443.
  47. Koyama T, McHaffie JG, Laurienti PJ, Coghill RC (2005) The subjective experience of pain: Where expectations become reality. PNAS 102: 12950-12955.
  48. Mellers B, Schwartz A, Ritov I (1999) Emotion-based choice. J Exp Psychol Gen 128: 332-345.
  49. Summerfield C, Trittschuh EH, Monti JM, Mesulam MM, Egner T (2008) Neural repetition suppression reflects fulfilled perceptual expectations. Nat Neurosci 11: 1004-1006.
  50. Seymour B, McClure SM (2008) Anchors, scales and the relative coding of value in the brain. Current Opinion in Neurobiology 18: 173-178.
  51. Abler B, Erk S, Herwig U, Walter H (2007) Anticipation of aversive stimuli activates extended amygdala in unipolar depression. J Psychiatr Res 41: 511-522.
  52. Carver CS, Scheier MF (2005) Optimism. In: Snyder CR, Lopez SJ, eds. Handbook of Positive Psychology. New York: Oxford University Press. pp 231-243.
  53. Solomon RL, Corbit JD (1974) An opponent-process theory of motivation: I. Temporal dynamics of affect. Psychol Rev 81: 119-145.