Next-generation sequencing of the CHO cell transcriptome (original) (raw)

Into the unknown: expression profiling without genome sequence information in CHO by next generation sequencing

Torsten Schulz

Nucleic Acids Research, 2010

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Developing genomic platforms for Chinese hamster ovary cells

Peter Nissom

Biotechnology Advances, 2009

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Meta-analysis of publicly available Chinese hamster ovary (CHO) cell transcriptomic datasets for identifying engineering targets to enhance recombinant protein yields

Linas Tamošaitis

Biotechnology journal, 2018

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Identifying key signatures of highly productive CHO cells from transcriptome and proteome profiles

Robin Philip

Microbial Cell Factories, 2006

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Transcriptome and proteome profiling to understanding the biology of high productivity CHO cells

Peter Nissom

Molecular …, 2006

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Application of System Biology Tools for the Design of Improved Chinese Hamster Ovary Cell Expression Platforms

Vijeta Sharma

Journal of Bioprocessing & Biotechniques, 2016

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Comparative proteomic analysis of three Chinese hamster ovary (CHO) host cells

Lufang Zhou

Biochemical Engineering Journal, 2017

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Transcription Profiling of Different Recombinant CHO Clones Based on Cross-species Microarray Analysis

Renate Kunert

Cell Technology for Cell Products, 2007

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PTSelect™: A post-transcriptional technology that enables rapid establishment of stable CHO cell lines and surveillance of clonal variation

Vandhana Chari

Journal of Biotechnology, 2021

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Transcriptional profiling of phenotypically different Epo‐Fc expressing CHO clones by cross‐species microarray analysis

Renate Kunert

Biotechnology Journal, 2008

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In search of expression bottlenecks in recombinant CHO cell lines—a case study

Renate Kunert

Applied Microbiology and Biotechnology, 2014

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A Comparative Transcriptomics Workflow for Analyzing Microarray Data from CHO Cell Cultures

Brian Follstad

Biotechnology journal, 2017

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A Consensus Genome-scale Reconstruction of Chinese Hamster Ovary Cell Metabolism

Ziomara Gerdtzen

Cell systems, 2016

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Genomic landscapes of Chinese hamster ovary cell lines as revealed by the Cricetulus griseus draft genome

Chao Bian

Nature Biotechnology, 2013

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Study of expression systems for large-scale protein production in CHO cells

Pedro Menvielle

2017

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Computational identification of microRNA gene loci and precursor microRNA sequences in CHO cell lines

Johannes Grillari

Journal of Biotechnology, 2012

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Microarray expression profiling identifies genes regulating sustained cell specific productivity (S-Qp) in CHO K1 production cell lines

Mohammed Bangash

Biotechnology Journal, 2012

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A comprehensive transcriptomic analysis of infant and adult mouse ovary

Linlin Pan

Genomics, proteomics & bioinformatics, 2014

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Generation of genetically engineered CHO cell lines to support the production of a difficult to express therapeutic protein

Sandrine Romand, Anett Ritter

BMC Proceedings, 2013

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Single‐cell transcriptome analyses reveal heterogeneity in suspension cultures and clonal markers of CHO‐K1 cells

norichika ogata

Biotechnology and Bioengineering, 2020

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Reducing recombinant protein expression during CHO pool selection enhances frequency of high-producing cells

Bernard Massie

Journal of Biotechnology, 2019

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Systematically gap-filling the genome-scale model of CHO cells

Zerong Li

2020

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Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation

Johannes Grillari

Applied Microbiology and Biotechnology, 2014

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Mammalian systems biotechnology: An integrative framework for combining in silico modeling and multi-Omics datasets in different CHO parental cell lines

Kok Siong Ang

2016

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Dynamic mRNA and miRNA profiling of CHO‐K1 suspension cell cultures

Niraj Kumar

Biotechnology Journal, 2011

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The role of the cell cycle in determining gene expression and productivity in CHO cells

Mohamed al-Rubeai

Cytotechnology, 1999

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Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis

Renate Kunert

Biotechnology journal, 2018

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Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia

Piero Carninci

2003

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