Assessment of cadaveric livers discarded from transplantation. A correlation between clinical and histological parameters (original) (raw)

Annals of transplantation: quarterly of the Polish Transplantation Society

Abstract

We designed a study with the following aims: to assess tissue quality of 100 cadaveric livers discarded from transplantation, to identify discarded organs which could have been used either for transplantation or for isolation of hepatocytes, to assess donor clinical factors which may impact the histology. Liver wedge biopsies were performed during kidney procurement, sent for processing and data interpretation. In 46% of the evaluated tissues severe changes were found; these organs according to pathologists were "not suitable for transplantation". In 19% less pronounced changes classified organs as "probably not suitable for transplantation". In 35% biopsies only minimal changes were found; these organs were classified as "probably suitable for transplantation" and could have been harvested as marginal organs or at least used for hepatocytes isolation. Results of biopsies suggested that approximately in one third of livers discarded from transplantation...

Magdalena Durlik hasn't uploaded this paper.

Let Magdalena know you want this paper to be uploaded.

Ask for this paper to be uploaded.