Changes in Metabolic Profile Among Antiretroviral-Naive Patients Initiating Protease Inhibitor Versus Non–Protease Inhibitor Containing HAART Regimens (original) (raw)

JAIDS Journal of Acquired Immune Deficiency Syndromes, 2003

Vandana Menon

Oliver Ong

Augustus White

Abstract

Lipodystrophic syndrome, insulin resistance, and frank diabetes are emerging as important metabolic consequences of protease inhibitor (PI) therapy in patients with HIV. 1-3 These metabolic abnormalities may be due to direct effects of PI on rates of whole body lipolysis, differentiation and ...

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