[Analysis of factors associated to failure of medical treatment of amoebic liver abscess] (original) (raw)

[Nitric oxide participation during amoebic liver abscess development]

Medicina, 2007

Nitric oxide participates in both physiological and pathophysiological functions, and it plays an important role in the mammalian immune system in killing or inhibiting the growth of many pathogens, including parasites, viruses and bacteria. Entamoeba histolytica is a protozoan parasite that causes amoebiasis, which is characterized by intestinal damage and amoebic liver abscess development. The development of amoebic liver abscess in hamsters is similar to that in humans, whereas mice are resistant to amoebic liver abscess development due to an increase in nitric oxide production. Unlike in mice, amoebic liver abscess development in hamsters is due to an excess in nitric oxide production or possibly to a greater susceptibility of the hamster to damage caused by nitric oxide. Therefore, it could be important to elucidate if, in humans, an excess in nitric oxide production favors amoebic liver abscess development.

A diagnostic approach to hepatic abscess

Revista médica de Chile (Impresa), 2003

The non invasive diagnosis of amebic liver abscess allows the use of empirical therapy without the requirement of invasive diagnostic procedures. To determine the discriminatory capacity of clinical, laboratory and ultrasound studies for the etiological diagnosis of liver abscess. Sixty one patients were initially included in this prospective study, but 12 did not comply with the inclusion criteria. Of the rest, 29 (59%) had an amebic liver abscess, 16 (33%) had a pyogenic liver abscess and four (8%) had an abscess of mixed etiology. Blood cultures were done in 42 patients. Ultrasound guided needle aspiration was done in 7 patients with amebic liver abscess and 13 patients with non amebic liver abscess. The clinical picture and ultrasound findings were similar in all types of amebic abscess. ELISA test for IgG anti-Entamoeba histolytica antibodies were positive in 100% of patients with amebic liver abscess. Antibodies measured by gel diffusion were positive in 93%. All patients with...

Pyogenic liver abscess. Presentation of a case

Revista Información Científica , 2021

The clinical case of a 79-year-old man with chronic alcoholism and other associated comorbidities presented, admitted with a fever of three days of evolution and suspected diagnosis of dengue at the Hospital Clínico Quirúrgico Docente “Dr. Ambrosio Grillo Portuondo”, from Santiago de Cuba province. By multidisciplinary consensus, a pyogenic liver abscess of subsegments VII-VIII of the liver was diagnosed. An emergency laparotomy was performed with drainage of the purulent collection. He presented superficial infection of the surgical site, but the postoperative evolution was satisfactory and he was discharged cured 7 days later.

[Hepatic abscess: series of 107 cases and literature review]

Revista chilena de infectologia: organo oficial de la Sociedad Chilena de Infectologia

Liver abscess is a rare disease with high morbidity and mortality. Description of liver abscess cases attended in the Universidad de Chile Clinical Hospital between 2000 and 2007 and review of the literature on the topic. For 107 cases reviewed, mean age was 59 years. Most common symptoms were fever and abdominal pain with an average duration of 19 days. COMORBIDITY: twenty five percent of patients had Diabetes Mellitus type 2, seven percent were immunosuppressed patients and 24% had undergone invasive procedures. Not achieved identify the origin in most cases. The most requested image test was abdominal CT. In 49/75 (65.3%) the abscess culture allowed to establish the etiology. Bacteremia was present in 17/68 (25%) of cases. Most cases were treated with two or more antibiotics and percutaneous drainage. Clinical manifestations and resolution of liver abscess in this series are consistent with those described in the literature.

[Descriptive analysis of 41 patients with a pyogenic hepatic abscess]

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

To identify the clinical, laboratory and imaging characteristics of 41 patients with a pyogenic hepatic abscess. Retrospective, descriptive. Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán. 41 patients with a pyogenic hepatic abscess. The measurement of the following variables was carried out: previous background, period of evolution, symptoms, signs, laboratory studies, imaging, treatment, complications and evolution. 41 patients were evaluated. The average age of the group was 52.5 years (SD = 14.3) and 30 (73%) were male. The most frequent associated disease was diabetes mellitus which was found in 15 patients (37%). The most frequent clinic data were: fever in 38 patients (93%), chills in 26 (63%) and pain in the upper right quadrant in 25 (61%). The most common source of the formation of the abscess was of biliary origin in six patients (15%) and the serum amoeba test was positive in 10% of the cases. The localization of the abscess in our series was as follows: 33 cases (81%) were from the right lobe, five (12%) from the left lobe, three (7%) from both lobes and 87% were solitary. The germ found more frequently was E. coli in five patients (15%). As for the treatment, puncture by computed tomography was carried out in 25 patients (61%), four patients had a surgery and the rest were treated only with antibiotics. Regarding mortality, only one patient died (2%) due to a septic shock. An association with diabetes mellitus was identified and the most frequent origin was biliary, these data have already been reported in other studies. On the other hand, mortality and morbidity rates in our study were low.

[Pyogenic liver abscess in children: clinical experience in a pediatric reference center]

Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia, 2017

Liver abscess is a serious and an uncommon pediatric disease. Description of 20 pediatric patients with liver abscess admitted in "Ricardo Gutierrez" Children's Hospital, a Tertiary Reference Center of Buenos Aires, between 2009 and 2015. The hospitalization rate was 35/100.000 admissions. Median age was 5 years old, male/female ratio 4/1. Five patients (25%) had predisposing factors. Median days at diagnosis were 12. Fever 100%, prolonged fever 60%, abdominal pain 50%. The majority had leukocytosis and elevated CRP (median 160 mg/L). Liver enzymes were elevated in only 40% of patients. Ultrasonography detected 90%. A single abscess was observed in 60%; localized at right hepatic lobe, 65%. Purulent material was positive in 12/17 (70%) and bacteremia was present in 3/20 (15%). Wide empirical antibiotic therapy was used. Treatment shift was needed in four patients. The median days of intravenous antibiotics were 30 and the median of total treatment were 53. Surgical pro...

[Visceral larva migrans syndrome and hepatic abscess: A case report]

Archivos argentinos de pediatria, 2018

Toxocariasis canis or catis is a zoonotic infection disseminated in humans. Human beings can act as non-natural hosts in which the parasite can survive for long periods of time and they become infected by the ingestion of geohelminth eggs. These can be located on the ground, playgrounds and children's games, and are mostly eliminated by dogs or cats. There are different spectra in the clinical presentation of this infection, which can vary from an asymptomatic host to the production of serious organic lesions; some of them are ocular toxocariasis, visceral larva migrans, covert toxocariasis and neurotoxocariasis. In this case report a patient who presents with a history of respiratory problems, prolonged fever, and hepatomegaly. Laboratory analyses show hypereosinophilia, hypergammaglobulinemia and serodiagnosis is positive for toxocariasis. Preliminary diagnosis: Visceral Larva Migrans Syndrome.