A Review on Pharmacological and Phytochemical Profile of Asparagus racemosus Willd (original) (raw)
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ETHNOPHARMOCOLOGICAL REVIEW OF ASPARAGUS RACEMOSUS WILLD
This paper presents review of studies conducted on the pharmacological activities of Asparagus racemosus keeping in the view fifteen different properties which deals with effects on neurological disorder, phytoestrogen, antidirrhoeal, antidyspepsia, adaptogenic, antiulcerogenic, antioxidants, cardio protection, antibacterial, immunoadjuvent, antitussive, styptic, geriatric tonic, anti-diabetic and aphrodisiac. These data presented along with experimental model in which studies were conducted; the formulation/extract which are tested, the mode of actions and their effects are being mentioned Key Words:-Demulcent, Diuretic, Aphrodisiac, Galactagogue , Phytoestrogen, Menopause. Introduction:-Asparagus racemosus Willd. (Family Asparagaceae; Liliaceae) is an important medicinal plant of tropical and subtropical India. Its medicinal usage has been reported in the Indian and British Pharmacopoeias and in traditional systems of medicine such as Ayurveda, Unani and Siddha. The plant enjoys considerable reputation in Indian system of medicine.Asparagus racemosus Willd.
Asparagus racemosus: The plant with immense medicinal potential
Journal of Pharmacognosy and Phytochemistry, 2018
The genus Asparagus belonging to the family liliaceae. The Asparagus racemosus (Shatavari or Sanspayein) is most commonly distributed species in tropical and subtropical regions of India. The folk use of Shatavari has been mentioned in traditional medicine system such as Unani & Siddh in folk and ayurvedic system British & Indian Pharmacopeias and is widely used shrub important for its sapogenin content which is the precursor of many pharmacologically active steroids. It is thought that almost all of its parts having pharmaceutical properties but roots stem and leaves are the most important parts which are used medicinally. The Shatavari is used as, "Rasayanas" to enhance the body resistance against infections and improve the immune system. It is widely used for the treatment of various ailments as it contains many different phytochemicals. The notable medicinal properties of Shatavari are antispasmodic, anti-oxidant, anti-diabetic, anti-allergic, anti-malarial, heap to protective, anti-neoplastic activities, enhance immune resposes, anti-arthritic, antiinflammatory, anti-periodic, Antiulcerogenic action, immune modulatory antistress, Anti-diarrhoeal, Antidepressant, anti-leprotic, anti-abortifacient activity, antibacterial, antipyretic and analgesic. The purpose of this review to evaluate and explore the information about chemical constituent and its pharmacological activities for further unexplored areas in which Asparagus can be proved to have potential to cure diseases.
Investigation Of Analgesic And Neuropharmacological Activities of Asparagus racemosus Root Extracts
2012
Bangladesh due to possessing high medicinal value. It is an all-round tonic and rejuvenative which can be given to a person with any type, constitution, males or females, youngsters or elders. Indeed, Shatavari is the Universal Rasayana. The name Shatavari is symbolic which means one who possesses one hundred husbands .The plant is widely used in diarrhoea and dysentery. It also possesses anthelmintic and antiseptic properties (Sinha and Biswas,2011). The root extract of has been used in ulcer, diabetes and immunomodulation. Several nervous disorders, dyspepsia, tumors, inflammation, neuropathy, hepatopathy, cough, bronchitis, hyperacidity and certain infectious diseases can also be treated by this medicinal plant. The modulatory activity of has been observed on plasma glucose, insulin, insulin resistance index and metabolic liver enzymes in young and aged rats (Velavan and Begum, 2007).In addition to this, methanol root extract of shows cerebroprotective activity due to reduction of oxidative
International Journal of Herbal Medicine, 2016
Aromatic and medicinal plants have played key roles in the lives of tribal peoples living in the Himalaya by providing products for both food and medicine. Asparagus racemosus (Asparagaceae) is an important medicinal plant of tropical and subtropical India. Its medicinal usage has been reported in the Indian and British Pharmacopoeias and in traditional systems of medicine such as Ayurveda, Unani and Siddha. Asparagus racemosus has been described to use as antioxidant, immune stimulant, anti-dyspepsia and anti-tussive effects. It is also useful in treatment of epilepsy, kidney disorders, chronic fevers, excessive heat, stomach ulcers and liver cancer, increases milk secretion in nursing mothers and regulates sexual behaviors. The major active constituents of Asparagus racemosus are steroidal saponins. Isoflavones, asparagamine, racemosol, polysaccharides, mucilage, vitamins A, B1, B2, C, E, Mg, P, Ca, Fe, and folic acid present in roots. Other primary chemical constituents of Aspara...
Object: The object of the present paper is pharmacological screening of Asparagus Racemosus and evaluated for the antioxidant and anti-inflammatory potential by Ex-vivo method. Materials and method: The crude extract of Asparagus Racemosus was extracted out by the Soxhlet process. The quantitative chemical analysis was performed for the quantification and quality of active constituent. The antioxidant and anti-inflammatory activity of ethanolic extract of plant was determined using ex-vivo model. Antioxidant activity is assessed by the Hydrogen peroxide scavenging and reducing power assay method and Antiinflammatory activity determined by the Protein denaturation assay. Result and Discussion: The extract of Asparagus Racemosus was used for phytochemical constituent estimation and qualitative analysis. The Plant extract shown the sign of the alkaloid, saponin and tannins content. The ethanolic extract was found to be as tannin (15.12%), saponin (10.25%) and alkaloid (8.26%). The maximum hydrogen peroxide scavenging activity shown by ethanolic extract of Asparagus Racemosus was found to be 67.94 % at 400 µg/ml. In protein denaturation assay result stated that diclofenac sodium possesses maximum percentage of inhibition. The ethanolic extract of the plant Asparagus Racemosus possess significant inhibition activity at concentration 100, 200 and 400 µg/ml. Conclusion: The ethanolic extract of Asparagus Racemosus showed dose dependent hydrogen peroxide scavenging activity. Reducing power of ethanolic extract of Asparagus Racemosus significantly increased with increasing concentration. The in-vitro anti-inflammatory potential of ethanolic extract of Asparagus Racemosus had shown concentration dependent inhibition of protein denaturation. The plant Asparagus Racemosus has shown promising antioxidant and anti-inflammatory activity without any side effects and will be beneficial for society and industry with standardization approaches.
Phytochemical studies and in vitro activity of Asparagus racemosus
Journal of Nepal Pharmaceutical Association, 2012
Phytochemical and biological screening of root of Asparagus racemosus was studied. The brine shrimp bioassay of its various extracts showed that the methanol (MeOH) extract was biologically active. The column chromatography of hexane, acetone and methanol extracts resulted in the isolation of 9- hexadecanoic acid-9-octadecenylester (Z,Z), ?-Sitosterol, stigmasterol-3-O-?-D-glucopyranoside and diosgenin. The estimation of saponin in the root of Asparagus racemosus has also been carried out.DOI: http://dx.doi.org/10.3126/jnpa.v26i1.6632JNPA. XXVI(1) 2012 48-53
ASPARAGUS RACEMOSUS: FOR MEDICINAL USES & PHARMACOLOGICAL ACTIONS.
Asparagus racemosus, traditionally known as shatavari means \"Who possesses a hundred husbands or acceptable to many, family Liliaceae Shatavari found at low altitude throughout india.the dried root of plant are used as drug. Its content sapogenin, sarsasapogenins, flavonoids (kaempferol, quercetin , and rutin) and poly phenols is the precursor of many pharmacologically active steroids. It is used as medicine like in Ayurveda, Unani & Siddha. In Ayurveda it is considered as a female tonic and widely used in diseases including dysentery, in diabetic retinopathy, inflammations, tumor, bronchitis, nervous disorder, hyperacidity, certain infectious diseases, neuropathy, conjunctivitis, spasm, chronic fevers, and rheumatism. It is also beneficial in female infertility to increases libido and cures inflammation of sexual organs, enhances folliculogenesis and ovulation, prepares the womb for conception, prevents miscarriages, acts as post partum tonic by increasing lactation and normalizing the uterus and the changing hormones. Its used also indicate in leucorrhoea and menorrhagia. It has also been identified as one of the drug to controle the symptoms of AIDS. It also promotes maternal health, and fussily used as a galactagogue. Shatavari is the main Ayurvedic rejuvenative tonic for the females, as is Withania for the males. Its beneficial uses in correcting menstrual irregularities and they are prescribed by ayurvedic physicians to correct menstrual irregularities with products available in the markets.
Asparagus racemosus (Willd): Biological Activities & its Active Principles INTRODUCTION
Asparagus racemosus Willd. (Liliaceae) known as 'Shatavari'. The major active constituents of Asparagus racemosus are steroidal saponins (Shatavarins I-IV). Isoflavones, Asparagamine, Racemosol, Polysaccharides, mucilage, vitamins A, B 1 , B 2 , C, E, Mg, P, Ca, Fe, and folic acid present in roots. Other primary chemical constituents of Asparagus are essential oils, asparagine, arginine, tyrosine, flavonoids (kaempferol, quercetin, and rutin), resin, and tannin. It is a well known Ayurvedic rasayana which prevent ageing, increase longevity, impart immunity, improve mental function, vigor and add vitality to the body. It is also used in nervous disorders, dyspepsia, tumors, inflammation, neuropathy and hepatopathy.© 2011 IGJPS. All rights reserved
Pharmacognostical and Phytochemical evaluation of root of Asparagus racemosus Willd
Journal of Drug Delivery and Therapeutics
Aim of this is to examine the Pharmacognastical and Phytochemical properties of Asparagus racemosus. The qualitative microscopy, Phytochemical screening, physicochemical evolution, fluorescence analysis and HPTLC studies were carried out according to the standard procedure recommended in WHO guidelines. The root had compactly arranged, uniseriate, polygonal to radially elongated, thickwalled cell represent the outermost piliferous layer. Immediately laying below the epidermis is extensively developed, several layers of thick cortex made up of parenchymatous cells. The cortical cells contain raphide bundles. The innermost one or two layer of cortex immediately outside the endodermis comprises thick-walled cells, with the numerous oval or circular pits on their walls. Endodermis is composed of a single layer of compactly arranged, barrel-shaped parenchymatous cells. Inner to endodermis is a single layer of thin-walled, parenchymatous cells constituting the pericycle in the form of a ring, which surrounds a central stele. Phytochemical investigation of root shows total ash (6.5 %w/w), acid insoluble ash (1.3% w/w), and water-soluble ash (2.2% w/w). Loss on drying is (5.5% w/w). Cold extractive value in pet, ether (0.5%% w/w) in chloroform (3.4% w/w), methanol (8.0 % w/w) and in water (10.2% w/w). Hot extractive value in pet. ether (0.9% w/w), in chloroform (4.6 % w/w), methanol (10.40 % w/w) and in water (11.2% w/w). In methanolic extract and aqueous extract, tannins and saponins present in a major amount. Other constituents include carbohydrate, glycosides and phenolic compounds were present. Various pharmacognistical parameters evaluated in this study help in identification and standardization of the root of Asparagus racemosus.