Clinical Observations and Occurrence of Complications following Heavy Silicone Oil Surgery (original) (raw)
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Heavy silicone oil as a long-term endotamponade agent for complicated retinal detachments
BioMed research international, 2014
We retrospectively evaluated a heavy silicone oil (HSO) as a long-term intraocular endotamponade agent to treat complicated RD by inferior PVR in 25 eyes of 25 patients. Patients underwent PPV and injection of Oxane HD as an internal tamponade agent. A comparison of preoperative and postoperative BCVA at month 1, month 6, and last visit was made in the group in which HSO was removed and in the group in which HSO was not removed. Statistical calculations were performed using the Wilcoxon test. The HSO was removed from 11 patients after a mean of 26.55 ± 21.38 months. The HSO remained inside the vitreous cavity in 14 eyes due to a high chance of PVR recurrence (mean follow-up period, 11.07 ± 7.44 months). Anatomic success was achieved in 92%. The BCVA in the group, in which HSO was not removed, improved significantly during the first 6 months. Among the patients who had the oil removed, there was improvement in BCVA after 1 month. Oil emulsification was the most common adverse effect ...
Bali Journal of Ophthalmology, 2017
Objective: To observe the patient characteristics and complications after silicone oil removal, in vitrectomized patients with SO as an internal tamponade. Method: This study was designed for observational-descriptive of medical records vitrectomized patients with SO tamponade and subsequent removal in April 2011 to March 2012. Cases were classified into 2 groups between different viscosities (SO 1300 cSt and 5500 cSt). Furthermore, each group was then evaluated by anatomic improvement (attachment or redetachment) and complication rates after SO removal (cataract formation, glaucoma, SO emulsification). Result: The indications for the use of silicone oil were rhegmatogenous retinal detachment in 47 eyes (85.5%), 4 eyes (7.3%) were associated with proliferative vitreoretinopathy (PVR), 4 eyes (7.3%) had vitreous hemorrhage caused by AMD (1 eye) and 3 eyes had proliferative diabetic retinopathy with tractional retinal detachment. Silicone oil removal was done on average 118.87 days for SO 5500 cSt (range from 28 until 360 days) and average 116.25 days for SO 1300 cSt (range from 81 days until 185 days). After silicone oil removal, the retina remains attached in 50 (90.09%) of the eyes, 34% had visual acuity > 6/120 and 7.27 % had Intra Ocular Pressure (IOP) > 21 mmHg. Comparing 1000 cSt and 5000 cSt silicone oil-filled eyes, redetachment occurred more frequently in the latter group especially in cases with associated PVR. Conclusion: Rates of anatomical success from this study was 90.09%, but redetachment was found in 9.09% eyes. Several complications were found after SO removal such as cataract formation, glaucoma and SO emulsification.
Intraocular silicone oil removal: timing, outcome, and silicone oil complications encountered
Malaysian Journal of Ophthalmology, 2019
Introduction: Silicone oil is the preferred tamponade agent used in pars-plana vitrectomy for retinal detachment when a long duration of endotamponade is intended. Due to its possible long-term complications, removal of silicone oil (ROO) is recommended. Purpose: This study is done to evaluate the mean duration and complications of silicone oil tamponade, and the anatomical and visual outcomes after silicone oil removal. Study design: Retrospective study. Materials and methods: Retrospective review was done on 55 eyes of 55 patients, in which ROO was carried out at Hospital Sultanah Bahiyah in 2016 with a minimum six months follow-up postoperatively. Results: The duration of silicone oil tamponade in these eyes ranged from 1.0 to 55.5 months, with mean duration of 10.8 months (SD 7.74). Common complications of silicone oil tamponade observed were cataract in 30 eyes (54.5%), followed by secondary high intraocular pressure in 6 eyes (10.9%), and band keratopathy in 3 eyes (5.5%). Six...
Journal of Pakistan Medical Association, 2019
Silicone oil (SO) has a well-established role in vitreoretinal surgery and is successfully used in the management of complicated retinal detachments (RD). 1,2 In order to minimise complications associated with long-term use, SO is removed once retinal status appears stable. 3 Removal of silicone oil (ROSO) is associated with serious complications that include re-detachment of retina, hypotony, expulsive haemorrhage, vitreous haemorrhage and unexplained visual loss. 4,5 Residual vitreo-retinal traction, especially at vitreous base and re-proliferations, are most likely reasons for retinal re-detachment. It is most commonly seen during the first 10 days post-ROSO, and is reported in 2% to 40% cases. 6-11 ROSO through pars plana by active method has been one of the commonest methods performed. Trans conjunctival sutureless vitrectomy (TCSV) is a safe and effective technique, which makes sutureless active and passive three-port ROSO possible, and obviates the need for conjunctival peritomy and stitching of scleral ports. 12,13 The current study was planned to review the frequency and timing of the re-detachment of retina post-ROSO and to discuss the risk factors for this still unresolved complication in vitreoretinal surgery. Patients and Methods The retrospective study was conducted at one publicsector and one private-sector hospital in Karachi, and comprised data related to patients who underwent pars plana vitrectomy with silicone oil endotamponade for complicated retinal detachment and subsequent ROSO between 1996 and 2015. These surgeries were performed by a single surgeon at the Department of Ophthalmology,
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016
OBJECTIVE To compare the efficacy and complications of using 1000-centistoke versus 5000-centistoke silicone oil for complex retinal detachment repair. STUDY DESIGN Case series. PLACE AND DURATION OF STUDY LRBT Tertiary Eye Hospital, Karachi, from January 2007 to June 2013. METHODOLOGY Eighty-five eyes (85 patients) presenting with superior rhegmatogenous retinal detachments associated with PVR grades B and C (involving not more than 3 clock hours) were randomized to either 1000 centistokes (n=44) or 5000 centistokes (n=41) silicone oil group. All patients underwent 23-gauge pars plana vitrectomy surgery with silicone oil intraocular tamponade. Patient data was analysed at 18 months post-operatively. IBM SPSS 21 was used for data analysis. RESULTS There were 52 male and 33 female patients aged between 22 and 70 years (45.2 ±16.2). After the first surgery, successful reattachment of the retina was achieved in 67 eyes (78.8%); of which 35 eyes were in 1000-centistoke and 32 eyes in 50...
Heavy and standard silicone oil: intraocular inflammation
International Ophthalmology, 2017
Purpose Proliferative vitreoretinopathy in the inferior retina remains clinically challenging. Heavierthan-water intraocular tamponades have been developed to improve inferior tamponading properties, and their chemical compositions have been substantially improved over the years, in parallel with developments in vitrectomy instrumentation and surgical techniques. Herein we present an updated review of the clinical use of standard formulations and HSO, focusing on analysis of the intraocular inflammation associated with endotamponade agents, and comparison of the adverse effects of these agents on the physical and biological properties of the eye. Methods A detailed literature search was conducted on PubMed, EMBASE, Cochrane Library, and Google Scholar using the key words. Fifty-eight articles matched our inclusion criteria that were included in this systematic review. Results Perfluorocarbon liquids and partially fluorinated alkanes are associated with tamponade emulsification, intraocular inflammation, and rises in intraocular pressure, but these associations are not as strong when these substances are mixed with a heavy silicone oil (HSO). Two recently approved heavy silicone oil tamponades, Oxane HD and Densiron 68, are now available for use in clinical practice. While the complication spectrum of the new generation of these HSOs seems to be similar to that of conventional silicone oil tamponades, they provide better support for the inferior retina and the posterior pole. Conclusion Both regular and heavy silicone oils usually yield good success rates in cases of complicated retinal detachment. Decisions as to whether to utilize heavy or regular silicone oil should be made on a case-by-case basis.
Acta Ophthalmologica, 2020
Silicone oil (SO) has been used as a long‐term tamponade agent in the treatment of complicated vitreoretinal diseases for about half a century, during which time many advances in surgical techniques and technologies have been made. This review summarizes the chemical and physical properties of SO, its indications and complications, including particularly emulsification. The mechanisms and risk factors for emulsification are discussed, as well as novel strategies for its effective removal. Finally, the review focuses on new improved formulations of SO, including research into slow‐release pharmacological agents within SO and provides an overview of alternatives to SO for the purpose of long‐term tamponade that are being developed.
Intraocular pressure changes during and after silicone oil endotamponade (Review)
Experimental and Therapeutic Medicine, 2020
Silicone oil (SIO) has rapidly become an indispensable adjunct in vitreoretinal surgery. Constant improvements in purity and also in viscosity have not totally prevented specific complications that may occur during endotamponade. Results of in vitro studies that suggested that higher viscosity silicone oil might be superior in terms of stability and safety are confirmed in real life only if endotamponade lasts for more than 6 months. Intraocular pressure changes induced by the silicone oil endotamponade or oil extraction are documented from its very first use and are potentially threatening vision. The purpose of this review is to update current knowledge on the incidence, risk factors, pathogenesis, and management of secondary silicone oil glaucoma. Also, in a retrospective evaluation on cases with complex retinal detachments that underwent 23G vitrectomy and high viscosity SIO endotamponade, we have noticed that a considerable number of cases developed significant intraocular pressure changes during SIO endotamponade and after SIO removal, especially in early postoperative period. Contents 1. Introduction 2. Current state of knowledge regarding intraocular pressure changes during and after silicone oil endotamponade 3. Conclusions
Changes Of Intraocular Pressure In Vitrectomised Eyes After Removal Of Silicone Oil
Journal of Ayub Medical College, Abbottabad : JAMC, 2016
BACKGROUND Patients with Rhegmatogenous retinal detachment develop raised intraocular pressure (IOP) when they undergo pars plana vitrectomy with silicone oil. The present study was done to document changes in IOP with silicone oil and after its removal. METHODS The interventional study was conducted at Eye department of Lady Reading Hospital Peshawar, from August 2012 to July 2014 on 30 patients with Rhegmatogenous retinal detachment in whom pars plana vitrectomy with silicone oil injection was indicated. IOP readings were obtained on 1st postoperative day, at one month and at 6 months; the silicone oil was removed after the third reading and the IOP readings obtained after 2 weeks. RESULTS Of the 30 patients selected for the study, there were 25 (83.3%) males and 5 (16.7%) females with ages ranging from 12-80 years (mean age 41.83±21.43 years). The mean of three pre silicone oil removal IOP readings was 27.35±9.20 mmHgwhich was reduced to a mean of 16.10±6.14mmHg following the rem...