original ) (raw )Evidence that cyclic nucleotides activating rabbit muscle protein kinase I interact with both types of cAMP binding sites associated with the enzyme
Stein Doskeland
The Journal of biological chemistry, 1983
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(Rp)- and (Sp)-8-piperidino-adenosine 3',5'-(cyclic)thiophosphates discriminate completely between site A and B of the regulatory subunits of cAMP-dependent protein kinase type I and II
Hans-gottfried Genieser
European Journal of Biochemistry, 1994
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8-Substituted cAMP Analogues Reveal Marked Differences in Adaptability, Hydrogen Bonding, and Charge Accommodation between Homologous Binding Sites (AI/AII and BI/BII) in cAMP Kinase I and II †
Stein Doskeland
Biochemistry, 2000
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Quantitative structure-activity relations for the relative affinities of cAMP-derivatives with large substituents in positions 2 and 8 for the four different regulatory sites of a proteinkinase
Ludovic Kurunczi
European Journal of Plant Pathology, 1998
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Crystal Structures of RIα Subunit of Cyclic Adenosine 5‘-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with ( R p )-Adenosine 3‘,5‘-Cyclic Monophosphothioate and ( S p )-Adenosine 3‘,5‘-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP † , ‡
Xuong Nguyen-Huu , Lynn F Ten Eyck
Biochemistry, 2004
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The Major Catalytic Subunit Isoforms of cAMP-dependent Protein Kinase Have Distinct Biochemical Properties in Vitro and in Vivo
Michael Uhler
Journal of Biological Chemistry, 1996
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Substrate-mediated channeling of a chemical reagent to the active site of cAMP-dependent protein kinase
Philip A Gottlieb
FEBS Letters, 1981
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Adenine-arginine mimetics as bisubstrate analog inhibitors of cAMP-dependent protein kinase
Ibrahim Katampe
Bioorganic & Medicinal Chemistry Letters, 1996
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Binding of two fluorescent cAMP analogues to type I and II regulatory subunits of cAMP-dependent protein kinases
C. Mucignat
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1997
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Determinants of Ligand Binding to cAMP-Dependent Protein Kinase †
Volkhard Helms
Biochemistry, 1999
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Solution structure of synthetic peptide inhibitor and substrate of cAMP-dependent protein kinase. A study by 2D 1H NMR and molecular dynamics
J. Parello
The Journal of Peptide Research, 2009
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Synergistic Binding of Nucleotides and Inhibitors to cAMP-dependent Protein Kinase Examined by Acrylodan Fluorescence Spectroscopy
Igor Tsigelny
Journal of Biological Chemistry, 1997
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Kinetic analysis of inhibition of cAMP-dependent protein kinase catalytic subunit by the peptide–nucleoside conjugate AdcAhxArg6
Jaak Jarv
Bioorganic Chemistry, 2004
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CAMP-dependent protein kinase: prototype for a family of enzymes
J. Bubis
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1988
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Effect of cAMP and ATP on the reassociation of phosphorylated and nonphosphorylated subunits of the cAMP-dependent protein kinase from bovine cardiac muscle
Rafael Rangel-Aldao
The Journal of biological chemistry, 1977
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The rate of recombination of the subunits (RI and C) of cAMP-dependent protein kinase depends on whether one or two cAMP molecules are bound per RI monomer
Stein Doskeland
The Journal of biological chemistry, 1990
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Interaction of the regulatory subunit (RII) of cAMP-dependent protein kinase with RII-anchoring proteins occurs through an amphipathic helix binding motif
Ted Acott
Journal of Biological Chemistry, 1991
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Inhibition of nucleoside diphosphate kinase (NDPK/nm23) by cAMP analogues
Dirk Roymans
FEBS Letters, 1997
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Comparative Structure-Affinity Relations by MTD for Binding of Cycloadenosine Monophosphate Derivatives to Protein Kinase Receptors
Ludovic Kurunczi
Quantitative Structure-activity Relationships, 1995
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On the protein accommodating site of the catalytic subunit of adenosine cyclic 3′,5′-phosphate dependent protein kinase
Philip A Gottlieb
Biochemistry
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The inhibitory effect of cyclic AMP on phosphatidylinositol kinase is not mediated by the cAMP dependent protein kinase
Carlos Suarez-Quian
Biochemical and Biophysical Research Communications, 1987
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Signaling through cAMP and cAMP-dependent protein kinase: Diverse strategies for drug design
Natarajan Kannan
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2008
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Identification of phosphorylation sites in the recombinant catalytic subunit of cAMP-dependent protein kinase
Sean Bell
The Journal of biological chemistry, 1993
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Folding and activity of cAMP-dependent protein kinase mutants
Harald Schwalbe
FEBS Letters, 2005
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A point mutation abolishes binding of cAMP to site A in the regulatory subunit of cAMP-dependent protein kinase
J. Bubis
The Journal of biological chemistry, 1988
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A sequence variant in the N-terminal region of the catalytic subunit of the cAMP-dependent protein kinase
Herwig Ponstingl
FEBS Letters, 1989
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Characterization of PKIgamma , a Novel Isoform of the Protein Kinase Inhibitor of cAMP-dependent Protein Kinase
Michael Uhler
Journal of Biological Chemistry, 1997
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Purification and characterization of a dimer form of the cAMP-dependent protein kinase from mouse liver cytosol
Thomas Giannakouros
Molecular and Cellular Biochemistry, 1999
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Structure-Function Studies of the cAMP-Dependent Protein Kinase In Vitro and in Intact Cells
Gary Morris
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Modified cAMP Derivatives: Powerful Tools in Heart Research
János Magyar
Current Medicinal Chemistry, 2011
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Effects of cAMP-binding site mutations on intradomain cross-communication in the regulatory subunit of cAMP-dependent protein kinase I
Garth Ringheim
Journal of Biological Chemistry, 1990
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Formation of Inactive cAMP-saturated Holoenzyme of cAMP-dependent Protein Kinase under Physiological Conditions
Stein Doskeland
Journal of Biological Chemistry, 2002
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Dimerization/Docking Domain of the Type Ia Regulatory Subunit of cAMP-dependent Protein Kinase
Lili H.
1998
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