Subunits of the regulatory complex of the 26S protease (original) (raw)

Abstract

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The paper discusses the regulatory complex of the 26S protease, identifying its various subunits and examining their roles in the mechanism of degradation of ubiquitin-conjugated proteins. It highlights the distinctions between the 26S protease and its companion enzyme, the 20S proteasome, and suggests they share common subunits that influence their activities. The findings suggest a collaborative structure between the 26S protease and the 20S proteasome in the proteolytic pathway.

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