Vanishing Tumors of Thyroid: Histological Variations after Fine Needle Aspiration (original) (raw)

Abstract

Introduction: Fine needle aspiration cytology (FNA) of thyroid nodules can lead to changes that extensively replace cytologically confirmed thyroid lesions. These replaced thyroid lesions are called vanishing tumors, and can be challenging to pathologists, endocrinologists and surgeons, rendering the final pathological diagnosis difficult to interpret. We performed a retrospective analysis focusing on the issues that tend to compromise management plans for these vanishing tumors. Study Design: Retrospective review Methods: Data of 609 patients referred to our institution for thyroid surgery were reviewed. Patients with suspicious lesions on neck ultrasound underwent FNA biopsy. We compared FNA cytological and surgical pathological findings to identify patients with vanishing tumors. FNA-induced reactive changes such as cystic degeneration, hemorrhage, calcification, cholesterol crystals, fibrosis and granulation tissue were identified. Results: Seventeen patients (2.7%) were identif...

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