The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator.
Nicholas V Cozzi, Ph.D., Meyer Jackson, Arnold Ruoho
Science, 2009
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The Endogenous Hallucinogen and Trace Amine N,N-Dimethyltryptamine (DMT) Displays Potent Protective Effects against Hypoxia via Sigma-1 Receptor Activation in Human Primary iPSC-Derived Cortical Neurons and Microglia-Like Immune Cells
Attila Szabo
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The Protective Role of Dimethyltryptamine against Ischemia-Reperfusion Injury (book chapter in: Advances in Psychedelic Medicine: State-of-the-Art Therapeutic Applications; Publisher: Praeger, 2019; Editors: Michael J. Winkelman and Ben Sessa; pp. 214-231.)
Attila Szabo
Advances in Psychedelic Medicine: State-of-the-Art Therapeutic Applications, 2019
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Psychedelic N,N-Dimethyltryptamine and 5-Methoxy- N,N-Dimethyltryptamine Modulate Innate and Adaptive Inflammatory Responses through the Sigma-1 Receptor of Human Monocyte-Derived Dendritic Cells
Éva Rajnavölgyi, Attila Szabo
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Biosynthesis and extracellular Concentrations of N,N- dimethyltryptamine (DMt) in Mammalian Brain
Jon Dean
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When the Endogenous Hallucinogenic Trace Amine N,N-Dimethyltryptamine Meets the Sigma-1 Receptor
Teruo Hayashi
Science Signaling, 2009
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Psychedelics and immunomodulation: novel approaches and therapeutic opportunities
Attila Szabo
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N, N-Dimethyltryptamine (DMT), an Endogenous Hallucinogen: Past, Present, and Future Research to Determine Its Role and Function
steven barker
Frontiers in Neuroscience, 2018
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The in vitro identification of dimethyltryptamine (DMT) in mammalian brain and its characterization as a possible endogenous neuroregulatory agent
samuel christian
Biochemical Medicine, 1977
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implications for optimizing plant breeding and cultivation strategies. Supporting Online Material The Hallucinogen N,N-Dimethyltryptamine (DMT) Is an Endogenous Sigma-1 Receptor Regulator
Vases Jorgy
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Metabolism of the hallucinogen N,N-dimethyltryptamine in rat brain homogenates
samuel christian
Biochemical Pharmacology, 1980
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Impact of Two Neuronal Sigma-1 Receptor Modulators, PRE084 and DMT, on Neurogenesis and Neuroinflammation in an Aβ1-42-Injected, Wild-Type Mouse Model of AD
Botond Penke
International Journal of Molecular Sciences, 2022
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N,N-Dimethyltryptamine attenuates spreading depolarization and restrains neurodegeneration by sigma-1 receptor activation in the ischemic rat brain
Nicholas V Cozzi, Ph.D., Tímea Körmöczi, Dóra Hantosi, Rita Frank, Szilvia Kecskés
Neuropharmacology, 2021
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Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
Gabriella Gobbi
Pharmacological Reviews, 2020
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Effects of psilocybin, psychedelic mushroom extract and 5-hydroxytryptophan on brain immediate early gene expression: Interaction with serotonergic receptor modulators
Meitar Grad
Frontiers in pharmacology, 2024
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The protective role of dimethyltryptamine and its analogues against ischemiareperfusion injury: Commentary
Ede Frecska
Neuroscience Chronicles, 2021
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Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine
Sidarta Ribeiro
2017
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Faculty Opinions recommendation of Chronic, Intermittent Microdoses of the Psychedelic N,N-Dimethyltryptamine (DMT) Produce Positive Effects on Mood and Anxiety in Rodents
Genoveva Uzunova
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2020
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Psychedelic 5-Methoxy-N,N-dimethyltryptamine: Metabolism, Pharmacokinetics, Drug Interactions, and Pharmacological Actions
Emmanuel Mendoza Ibarra
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Modern views on an ancient chemical: Serotonin effects on cell proliferation, maturation, and apoptosis
Efrain Azmitia
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Dimethyltryptamine and other hallucinogenic tryptamines exhibit substrate behavior at the serotonin uptake transporter and the vesicle monoamine transporter
Paul Daley, Arnold Ruoho
Journal of Neural Transmission, 2009
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Agonist Properties of N,N-Dimethyltryptamine at Serotonin 5-HT2A and 5-HT2C Receptors
Randy Smith
Pharmacology Biochemistry and Behavior, 1998
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The clinical pharmacology and potential therapeutic applications of 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT)
Attila Szabo, Rafael Lancelotta
Journal of Neurochemistry, 2022
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The Effects of Hallucinogens on Gene Expression
David Martín
Current topics in behavioral neurosciences, 2017
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Biochemical, Behavioral, and Pharmacologic Studies of the Effects of Dihydroxytryptamines in the Rodent Brain
Ross Baldessarini
Annals of the New York Academy of Sciences, 1978
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N,N-dimethyltryptamine and Amazonian ayahuasca plant medicine
Joachim Keppler
Human Psychopharmacology: Clinical and Experimental, 2022
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