Human biomonitoring of phthalate exposure in Austrian children and adults and cumulative risk assessment (original) (raw)
International journal of hygiene and environmental health, 2015
Abstract
Phthalates are a class of chemicals widely used as plasticisers in a multitude of common consumer products. Through contact with such products, people are regularly exposed to phthalates, which are suspected to contribute to adverse health effects, particularly in the reproductive system. In the present study, 14 urinary phthalate metabolites of 10 parent phthalates were analysed by HPLC-MS/MS among the Austrian population aged 6-15 and 18-81 years in order to assess phthalate exposure. In the total study population, ranges of urinary phthalate metabolite concentrations were n.d.-2,105μg/l (median 25μg/l) for monoethyl phthalate (MEP), n.d.-88μg/l (10μg/l) for mono-n-butyl phthalate (MnBP), n.d.-248μg/l (28μg/l) for mono-isobutyl phthalate (MiBP), n.d.-57μg/l (1.8μg/l) for mono-benzyl phthalate (MBzP), n.d.-20μg/l (n.d.) for mono-(2-ethylhexyl) phthalate (MEHP), n.d.-80μg/l (2.6μg/l) for mono-(2-ethyl-5-hydroxyhexyl) phthalate (5OH-MEHP), n.d.-57μg/l (1.9μg/l) for mono-(2-ethyl-5-ox...
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