Transcriptional regulation of the human FPR2/ALX gene: evidence of a heritable genetic variant that impairs promoter activity (original) (raw)

Anti-inflammatory circuitry: Lipoxin, aspirin-triggered lipoxins and their receptor ALX

Charles Serhan

Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005

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Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution

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Prostaglandins, Leukotrienes and Essential Fatty Acids, 2005

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Selectivity of Recombinant Human Leukotriene D4, Leukotriene B4, and Lipoxin A4 Receptors with Aspirin-Triggered 15-epi-LXA4 and Regulation of Vascular and Inflammatory Responses

Charles Serhan

The American Journal of Pathology, 2001

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Phosphorylation of 5-Lipoxygenase at Ser523 by Protein Kinase A Determines Whether Pioglitazone and Atorvastatin Induce Proinflammatory Leukotriene B4 or Anti-Inflammatory 15-Epi-Lipoxin A4 Production

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The Journal of Immunology, 2008

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Characterization of the Promoter and the Transcriptional Regulation of the Lipoxin A4 Receptor (FPR2/ALX) Gene in Human Monocytes and Macrophages

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The Journal of Immunology, 2012

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Aspirin-triggered 15-Epi-Lipoxin A4 (LXA4) and LXA4 Stable Analogues Are Potent Inhibitors of Acute Inflammation: Evidence for Anti-inflammatory Receptors

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Journal of Experimental Medicine, 1997

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Lack of activity of 15-epi-lipoxin A4 on FPR2/ALX and CysLT1 receptors in interleukin-8-driven human neutrophil function

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Clinical and Experimental Immunology, 2013

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Evidence for an Anti-Inflammatory Loop Centered on Polymorphonuclear Leukocyte Formyl Peptide Receptor 2/Lipoxin A4 Receptor and Operative in the Inflamed Microvasculature

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The Journal of Immunology, 2011

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Lipid-derived mediators in endogenous anti-inflammation and resolution: lipoxins and aspirin-triggered 15-epi-lipoxins

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TheScientificWorldJournal, 2002

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Anti-inflammatory actions of lipoxin A4 and aspirin-triggered lipoxin are SOCS-2 dependent

James Johndrow

Nature Medicine, 2006

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Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation

Ulf Hedin

International journal of cardiology, 2015

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Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side

Charles Serhan

Archivum immunologiae et therapiae experimentalis, 2001

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Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation

Charles Serhan

Journal of Experimental Medicine, 2000

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Heterologously expressed formyl peptide receptor 2 (FPR2/ALX) does not respond to lipoxin A4

Bernard Pirotte

Biochemical Pharmacology, 2013

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Opposing regulation of neutrophil apoptosis through the formyl peptide receptor-like 1/lipoxin A4 receptor: implications for resolution of inflammation

János Filep

Journal of Leukocyte Biology, 2008

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Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1 -initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine-Chemokine Axis

Charles Serhan

Journal of Experimental Medicine, 1999

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Lipoxin (LX)A4 and Aspirin-triggered 15-epi-LXA4 Inhibit Tumor Necrosis Factor 1α–initiated Neutrophil Responses and Trafficking: Regulators of a Cytokine–Chemokine Axis

Marc Pouliot

Journal of Experimental Medicine, 1999

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Aspirin (ASA) regulates 5-lipoxygenase activity and peroxisome proliferator-activated receptor alpha-mediated CINC-1 release in rat liver cells: novel actions of lipoxin A4 (LXA4) and ASA-triggered 15-epi-LXA4

Anna Planaguma

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002

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A novel rat lipoxin A 4 receptor that is conserved in structure and function

Charles Serhan

British Journal of Pharmacology, 2003

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Lipoxins, Aspirin-Triggered Epi-Lipoxins, Lipoxin Stable Analogues, and the Resolution of Inflammation: Stimulation of Macrophage Phagocytosis of Apoptotic Neutrophils In Vivo

Nicos A Petasis

Journal of the American Society of Nephrology, 2002

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Formation of Endogenous “Antiinflammatory” Lipid Mediators by Transcellular Biosynthesis

Charles Serhan

American Journal of Respiratory and Critical Care Medicine, 2000

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A Stable Aspirin-Triggered Lipoxin A4 Analog Blocks Phosphorylation of Leukocyte-Specific Protein 1 in Human Neutrophils

T. Ohira, G. Bannenberg, Charles Serhan

The Journal of Immunology, 2004

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Aspirin-triggered 15-epi-lipoxin A4 (ATL) generation by human leukocytes and murine peritonitis exudates: Development of a specific 15-epi-LXA4 ELISA

Nicos A Petasis

Prostaglandins & Other Lipid Mediators, 1999

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Aspirin-triggered lipoxin A4 and lipoxin A4 up-regulate transcriptional corepressor NAB1 in human neutrophils

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The FASEB Journal, 2001

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Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

Stefano Marullo, Charles Serhan

Nature Medicine, 2002

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Lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 inhibit peroxynitrite formation, NF- B and AP-1 activation, and IL-8 gene expression in human leukocytes

János Filep, Charles Serhan

Proceedings of the National Academy of Sciences, 2002

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Novel lipid mediator aspirin-triggered lipoxin A4 induces heme oxygenase-1 in endothelial cells

Christina Villela

American Journal of Physiology-cell Physiology, 2005

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