Chemo-enzymatic fluorination of unactivated organic compounds (original) (raw)
Use of fluorinated functionality in enzyme inhibitor development: Mechanistic and analytical advantages
kannan r
Journal of Fluorine Chemistry, 2008
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Fluorination methods in drug discovery
Sergio Bonesi
Organic & Biomolecular Chemistry, 2016
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Fluorine in Medicinal Chemistry
Bernd Kuhn
ChemBioChem, 2004
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Fluorobenzo[a]pyrenes as probes of the mechanism of cytochrome P450-catalyzed oxygen transfer in aromatic oxygenations
Ercole Cavalieri
Free Radical Biology and Medicine, 2003
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Tactical Applications of Fluorine in Drug Design and Development
Nicholas Meanwell
Fluorine in Heterocyclic Chemistry Volume 1, 2014
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Applications of Fluorine in Medicinal Chemistry
Elias Caracas
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Fluorinated substrate analogs as stereochemical probes of enzymic reaction mechanisms
Michael Marletta
Biochemistry, 1978
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Functionalization of Fluorinated Molecules by Transition-Metal-Mediated C–F Bond Activation To Access Fluorinated Building Blocks
Mike Ahrens
Chemical Reviews, 2015
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The role of fluorine in medicinal chemistry
Andrew Westwell
Journal of Enzyme Inhibition and Medicinal Chemistry, 2007
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Recent progress in the strategic incorporation of fluorine into medicinally active compounds
Iwao Ojima
Journal of Fluorine Chemistry, 2018
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Systematic Investigation of Lipophilicity Modulation by Aliphatic Fluorination Motifs
Jean-Yves Le Questel
Journal of Medicinal Chemistry, 2020
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Geometrically directed selective steroid hydroxylation with high turnover by a fluorinated artificial cytochrome P-450
Bartolo Gabriele
Tetrahedron Letters, 1998
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Recent Advances in Catalytic Enantioselective Fluorination Reactions
Sylvain Lectard
Advanced Synthesis Catalysis, 2010
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Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
nicholas meanwell
Journal of Medicinal Chemistry, 2018
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On the halofluorination reactions of olefins as selective, and an efficient methodology for the introduction of fluorine into organic molecules
Henryk Koroniak
Journal of Fluorine Chemistry, 2017
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Pyranoflavones: A Group of Small-Molecule Probes for Exploring the Active Site Cavities of Cytochrome P450 Enzymes 1A1, 1A2, and 1B1
Maryam Foroozesh
Journal of Medicinal Chemistry, 2013
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Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair
Gregory Fisher
Journal of biomolecular screening, 2015
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Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives
Rainer E . MARTIN
Chemical science, 2018
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Novel fluorinated antifolates. Enzyme inhibition and cytotoxicity studies on 2'- and 3'-fluoroaminopterin
Jack Henkin
Journal of Medicinal Chemistry, 1983
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Late stage fluorination: lessons to be learned from the fluorinase enzyme
Michelle Coote
2019
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Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach
Huzefa Raja
Journal of Natural Products, 2017
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18F-Fluorination: Challenge and Opportunity for Organic Chemists
riya halder
The Journal of Organic Chemistry
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Hydroxy-directed fluorination of remote unactivated C(sp3)–H bonds: a new age of diastereoselective radical fluorination
Andrea Zhu
Chemical Science
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Professor Norio Shibata, Nagoya Institute of Technology – Recipient of the 2019 American Chemical Society Award for Creative Work in Fluorine Chemistry
Joseph Thrasher
Journal of Fluorine Chemistry, 2020
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Fluorine important element in new drugs synthesis: Review Study
Ahmed A . J . Mahmood
Iraqi Journal of Pharmacy, 2018
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New Fluorination Methodology using a Hypervalent Fluoroiodane Reagent
Martyna Agneta Urbonaite
2020
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Fluoride elimination from substrates in hydroxylation reactions catalyzed by p-hydroxybenzoate hydroxylase
David Ballou
Journal of Biological Chemistry, 1980
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Selective Catalytic Hydrodefluorination as a Key Step for the Synthesis of Hitherto Inaccessible Aminopyridine Derivatives
Martin Studer
Angewandte Chemie International Edition, 2013
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Chemoselective fluorination of 2-hydroxy-3,4,7,8-tetrahydro-2H-chromen-5(6H)-ones using DAST
Gisele Paim, Jussara Navarini
Tetrahedron Letters, 2011
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Important fluorinated drugs in experimental and clinical use Authors proof20200710 18110 1ige75f
fyaz Ismail
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EWG assisted nucleophilic fluorination using PPHF: a strategy for the synthesis of 1,2,2-triaryl-2-fluoroethanones
Anil Kumar Pal
Tetrahedron, 2011
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Synthesis and Applications of Selected Fluorine-Containing Fluorophores
Maged Henary
Molecules
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Towards Greener Fluorine Organic Chemistry: Direct Electrophilic Fluorination of Carbonyl Compounds in Water and Under Solvent-Free Reaction Conditions
Stojan Stavber
Advanced Synthesis & Catalysis, 2010
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Fluorinase mediated chemoenzymatic synthesis of [18F]-fluoroacetate
Juozas Domarkas
Chemical Communications, 2010
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Enzyme inhibition by fluoro compounds
Theodore Alston
Journal of Biological Chemistry
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