Library of libraries: approach to synthetic combinatorial library design and screening of "pharmacophore" motifs (original) (raw)

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Comprehensive Survey of Combinatorial Library Synthesis: 2001

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Design of bioactive and structurally well-defined peptides from conformationally restricted libraries

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Peptide Diversity in Drug Discovery

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A paradigm for drug discovery employing encoded combinatorial libraries

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Beyond Mere Diversity: Tailoring Combinatorial Libraries for Drug Discovery

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Structurally homogeneous and heterogeneous synthetic combinatorial libraries

Viktor Krchnák

Molecular Diversity, 1996

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Efficient Discovery of Inhibitory Ligands for Diverse Targets from a Small Combinatorial Chemical Library of Chimeric Molecules

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Wei Zhou

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Targeted molecular diversity in drug discovery: Integration of structure-based design and combinatorial chemistry

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Libraries from libraries: generation and comparison of screening profiles

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Recent advances in the generation of chemical diversity libraries

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Drug Development Research, 1994

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Biosynthetic polypeptide libraries

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Versatility of positional scanning synthetic combinatorial libraries for the identification of individual compounds

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Evolving a Peptide: Library Platforms and Diversification Strategies

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The “One-Bead-One-Compound” Combinatorial Library Method

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Ligand-Based Peptide Design and Combinatorial Peptide Libraries to Target G Protein-Coupled Receptors

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Peptide Diversity in Drug Discovery SOLID-PHASE PEPTIDE SYNTHESIS

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Current challenges in peptide-based drug discovery

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Mixture-Based Combinatorial Libraries from Small Individual Peptide Libraries: A Case Study on α1-Antitrypsin Deficiency

Yi-Pin Chang

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A Method for Generation of Arbitrary Peptide Libraries Using Genomic DNA

Haiming Huang

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Sub-library composition of peptide libraries: Potential application in screening

Arpad Furka

Drug Development Research, 1994

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Synthesis and Screening of a Random Dimeric Peptide Library Using the One-Bead−One-Dimer Combinatorial Approach

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Integrating computational and mixture-based screening of combinatorial libraries

Adel Nefzi

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The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors

Victor Hruby

Bioorganic & Medicinal Chemistry Letters, 1993

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