Childhood microbial keratitis (original) (raw)

Microbial keratitis in children-A descriptive study

IP Innovative Publication Pvt. Ltd., 2017

Aim: The purpose of this study is to determine predisposing risk factors, microbiological profile and visual and structural treatment outcome of non viral microbial keratitis in children. Materials and Methods: A prospective case study of 52 eyes with microbial keratitis in a tertiary care teaching institute over a period of two years in children <16 years of age. Data was analyzed for patient demographics, culture data, management trends and visual and structural outcome of treatment. Results: Mean age of patients was 8.22 years ranging from 7 days to 14 years. The most common predisposing risk factor was trauma (57.69%), followed by malnutrition/Vitamin A deficiency (7.69%) unidentified causes accounted for 30.76% of cases. Cultures were taken from all patients. A total of 55.76% of eyes were culture positive.Bacterial isolates were seen in 30.76% of eyes, followed by fungi in 25% of the culture positive isolates. No growth in 44.23% of patients. Gram positive cocci(predominantly Staphylococcus aureus) were seen in 11.53% of isolates, and gram negative bacilli (predominantly Pseudomonas aerugionosa) in 19.23%. Fungi were identified in 25% of culture positive eyes with equal number of Aspergillus and Fusarium sp. Monotherapy with broad spectrum antibiotics was the preferred treatment. Final visual acuity on last follow up was < 6/60 in 20 eyes (62.5%) One patient each required therapeutic keratoplasty, conjunctival hooding and cyanoacrylate glue with bandage contact lens. Conclusion: Trauma was the predominant risk factor for microbial keratitis with Pseudomonas aeruginosa being the most common microorganism isolated. Majority of the cases responded to medical management.

Microbial Keratitis in Childhood

Ophthalmology, 1993

Background: Microbial keratitis occurs infrequently in childhood. The leading ocular predisposing factors are trauma and preexisting corneal disease. Many of the agerelated risk factors in adults playa minor role in children.

Microbial keratitis in children

Ophthalmology, 1998

Forty-seven eyes with microbial keratitis occurring in 44 children under 16 years of age were studied. Under the age of three, 92% of the infections involved Pseudomonas aeruginosa and/or various streptococcal species; later in childhood the typical adult pattern of infection was more common. Overwhelming systemic infections, malignant disease with orbital involvement and congenital ocular adnexal disease were important predisposing factors in the infant years; trauma and acquired external eye disease became increasingly important in mid-childhood. Surgery was necessary in 28% of the eyes. Frequent tearing and lack of patient cooperation preclude reliance on topical antibiotic therapy alone. Despite the difficulties, the mainstay of management involves daily biomicroscopic evaluation and regular subconjunctival antibiotic injections. The logistical problems of achieving these aims are discussed. [

Pediatric Microbial Keratitis: A Tertiary Care Center Report

Shiraz E-Medical Journal

Background: Microbial keratitis in children can cause visual loss and amblyopia. In this study, epidemiological features of microbial keratitis in children was examined at a tertiary care center in Iran. Methods: Sixty-three cases of microbial keratitis under the age of 15 admitted at Khalili hospital, Shiraz, Iran, during five years, were reviewed. Patients' age, gender, residential area, ulcer size, causative organism, surgical, and medical treatment were investigated. Results: Mean age of patients was 5.2 ± 4.8 years and 68.2% were under five years old. The prevalence of microbial keratitis was significantly higher in males than females (P = 0.003), especially in children coming from rural areas. Ulcers larger than 5 mm were observed more than smaller ones (P ≤ 0.0001) in hospitalized children. Ocular trauma was the most common risk factor (present in 56.9%), while in 22.4%, no risk factor was detected. The most causative microbial agent was Staphylococcus (42.8%). Fungus was detected in two cases and herpes simplex was suspected in eight cases. In 54% recovery was observed with medical therapy; mainly by combination of cefazolin-gentamicin and ceftazidime-vancomycin drops. Penetrating keratoplasty was needed in 16.9% and conjunctival flap in 14.7% of recalcitrant cases. Overall recovery from microbial keratitis was observed in 72% of cases, who showed complete healing of ulcer or significant decrease in size at the time of discharge from the hospital. Conclusions: Pediatric microbial keratitis was more common under the age of five years old and trauma was the main predisposing factor. Staphylococcus was the main causative microorganism and recovery was observed with topical treatment in the majority of cases. Trauma prevention and timely treatment is recommended.

Microbiological and epidemiological study of infectious keratitis in children and adolescents

Arquivos Brasileiros De Oftalmologia, 2016

Infectious keratitis is rare but potentially serious disease found mainly in young people. It is a preventable cause of visual impairment, similar to including amblyopia in children and mono-or bilateral blindness (1-3). More than one-third of eye injuries among children and adolescents result from their natural curiosity, immature motor skills, and tendency to imitate adult behavior without assessing the risks relevant to their actions. Although infectious keratitis is not common in this age group, it is potentially devastating as approximately, considering thet 30% of young victims of serious eye injuries end up with visual acuity lower

Microbial Keratitis

Ophthalmology, 2006

Purpose: To examine predisposing factors, treatment costs, and visual outcome of microbial keratitis in an ophthalmic casualty and inpatient population. Design: Retrospective medical records review. Participants: Fifteen-to 64-year-olds with microbial keratitis treated at the Royal Victorian Eye and Ear Hospital between May 2001 and April 2003 (n ϭ 291). Methods: Risk factors were identified from patient files. Demographic, clinical, and microbiological data; severity; outpatient visits; hospital bed days; and vision loss were examined. Main Outcome Measures: Cost to treat (Australian dollars), vision loss, and factors influencing these outcomes. Results: Ocular trauma (106/291 [36.4%]) and contact lens (CL) wear (98/291 [33.7%])

Microbial keratitis predisposing factors and morbidity

Ophthalmology, 2006

To examine predisposing factors, treatment costs, and visual outcome of microbial keratitis in an ophthalmic casualty and inpatient population. Retrospective medical records review. Fifteen- to 64-year-olds with microbial keratitis treated at the Royal Victorian Eye and Ear Hospital between May 2001 and April 2003 (n = 291). Risk factors were identified from patient files. Demographic, clinical, and microbiological data; severity; outpatient visits; hospital bed days; and vision loss were examined. Cost to treat (Australian dollars), vision loss, and factors influencing these outcomes. Ocular trauma (106/291 [36.4%]) and contact lens (CL) wear (98/291 [33.7%]) were the most commonly identified predisposing factors; 18 (6.1%) had multiple predisposing factors; 17 (5.8%), ocular surface disease; 20 (6.9%), herpetic eye disease; 4 (1.4%), systemic associations; 5 (1.7%), other; and 23 (7.9%), unknown cause. Of trauma cases, 90.6% involved males, compared with 44% to 57% for other group...