Effect of a sharp serum oestradiol fall before HCG administration during ovarian stimulation in donors (original) (raw)
2007, Reproductive BioMedicine Online
The current study evaluated how a sudden fall in serum oestradiol during ovarian stimulation in donors affects recipient outcome. After the assessment of pregnancy rate in cases of oestradiol falls of <10 or > or =10% (57.0 versus 45.6%), <20 or > or = 20% (55.2 versus 44.9%), <25 or > or =25% (57.2 versus 41.2%), and < 30 or > or =30% (57.1 versus 32.0%; P < 0.05), a significantly lower pregnancy rate was observed when the fall was…
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Revista Mexicana de Ciencias Pecuarias
Se comparó la tasa de gestación (TG) en vacas lecheras inseminadas a tiempo fijo mediante dos protocolos. El día 32 posparto, 275 vacas recibieron dos inyecciones de PGF2α con intervalo de 14 días. Doce días después de la segunda inyección, se asignaron a los siguientes tratamientos: 1) Ovsynch (n=144) recibieron GnRH; siete díasdespués PGF2α; 56 h más tarde GnRH y se inseminaron 16 h después 2) PRID5d (n=131) recibieron GnRH y un dispositivo intravaginal liberador de progesterona durante cinco días; al retirar el dispositivo, se aplicaron dosinyecciones de PGF2α con intervalo de 24 h; 56 h posterior al retiro del dispositivo, se aplicó GnRH y se inseminaron 16 h después. La gestación se diagnosticó por palpación rectal el día 45 posinseminación. Se comparó la TG mediante regresión logística. Las variables independientes fueron: tratamiento (Ovsynch vs PRID5d), producción láctea (≤40 vs >40 kg), técnico inseminador (1 vs 2), tipo de puerperio (normal vs anormal), partos previos ...
Human Reproduction, 1997
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Are pregnancy complications increased in poor responders?
Journal of the Turkish German Gynecological Association, 2011
To investigate whether pregnancy complications are increased in poor responders to ovarian stimulation in IVF treatment. Material and Methods: We reviewed the antenatal follow up and birth records of 26 poor responders to ovarian stimulation and 125 normoresponder patients in an IVF program. Results: Eighty nine (71.2%) of the normoresponders and 22 (84.6%) of the poor responders had no pregnancy complications. Gestational diabetes was present in 18 (14.4%) of the normoresponders and 3 (11.5%) of the poor responders. Seven of the normoresponders had placenta previa (5.6%). Two of the normoresponders (1.6%) had pregnancy induced hypertension. Two (1.6%) of the normoresponders had preeclampsia. One patient from each group had fetal anomaly (3.8% for poor responders vs. 0.8% for normoresponders). Cholestasis of pregnancy was present in two of the normoresponders (1.6%) and the 2 patients (7.7%) who delivered prematurely also belonged to this group. Conclusion: Our results revealed that pregnancy complications were not increased in patients with a reduced ovarian reserve when compared to their age matched counterparts.
Fertility and Sterility, 2001
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Recipient age and pulsatility index affect uterine receptivity in oocyte donation programmes
Reproductive BioMedicine Online, 2008
Successful embryo implantation depends on interactions between the embryo and the uterus. Investigating factors related to the recipients in an oocyte donation programme could therefore improve the overall pregnancy outcome. In this study, the factors that affect outcomes following IVF after oocyte donation were evaluated in a retrospective cohort study. A total of 143 cycles were evaluated. All oocyte donors were younger than 30 years of age. In the youngest recipients (&amp;amp;amp;amp;amp;amp;amp;lt; 34 years old) the implantation rate was higher (P = 0.042) and the abortion rate was apparently lower than in the recipients of more advanced age (&amp;amp;amp;amp;amp;amp;amp;gt; or =40 years old). The implantation and pregnancy rates were higher when the pulsatility index was &amp;amp;amp;amp;amp;amp;amp;gt; or = 3.0. The pulsatility index on the day of embryo transfer in oocyte donation IVF cycles was an important determinant of successful pregnancy outcomes.
Scholars International Journal of Obstetrics and Gynecology
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Human Reproduction
Serial serum levels of oestradiol, progesterone and the /3-subunit of human chorionk gonadotrophin (/3-HCG) had been performed in 674 cycles in women conceiving a singleton pregnancy, either spontaneously or as a result of assisted conception. To determine the value of these estimations in the prediction of early pregnancy loss, frequency distribution curves and receiver operating characteristic curves were derived for the respective hormones measured at weeks 4-7 of gestation and expressed as multiples of the median (MoM) values in pregnancies occurring both with and without ovarian stimulation. A cutoff level of 0-HCG < 0.5 MoM gave a sensitivity of 68% with an odds ratio of 4.0 at 7 weeks in unstimulated cycles in the prediction of pregnancy failure. A cutoff of 0.8 MoM for progesterone gave a sensitivity of 59% and an odds ratio of 2.8. Prospective hormonal monitoring during the early weeks of gestation may be useful in the prediction of early pregnancy loss and should help to avoid the emergency presentation of some of the complications of early pregnancy, in particular ectopic pregnancy. The limitations imposed by multiple pregnancies and uncertain gestation due to menstrual data may restrict the use of this strategy to specialist fertility centres.
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