An Alternative Procedure for the Aluminum-Mediated Conversion of Esters to Amides (original) (raw)

An Alternative Procedure for the Aluminum-Mediated Conversion of Esters to Amides

Synthetic Communications, 1982

Edward Turos

Steven Weinreb

Abstract

A convenient method has been developed for directly converting esters to amides using reagents derived from the reaction of trimethylaluminum with ammonium chloride, methylamine hydrochloride or dimethylamine hydrochloride.

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