Effect of mesenchymal stem cell penile transplantation on erectile signaling of aged rats (original) (raw)

The study investigates the effects of mesenchymal stem cell (MSC) transplantation on erectile dysfunction (ED) related to aging in rats. Evidence indicates that endothelial dysfunction plays a major role in ED, but MSC therapy may correct this through promoting vascular improvements and enhancing erectile signaling. Results show significant increases in intracavernosal pressure and smooth muscle cell regeneration post-transplantation, suggesting MSCs as a viable therapeutic option for age-related ED.