Prion Proteins and Neuronal Death in the Cerebellum
Saima Zafar
Prions - Some Physiological and Pathophysiological Aspects
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Molecular Mechanisms of Neurotoxicity of Pathological Prion Protein
Claudio Soto
Current Molecular Medicine, 2004
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Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis
Marcus Messenger
Journal of Biological …, 2005
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Prion Peptide Induces Neuronal Cell Death Through a Pathway Involving Glycogen Synthase Kinase 3.
Javier Diaz-Nido
Biochemical …, 2003
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Cytosolic Prion Protein (PrP) Is Not Toxic in N2a Cells and Primary Neurons Expressing Pathogenic PrP Mutations
Luana Fioriti
Journal of Biological Chemistry, 2005
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Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation
E. Quaglio, B. Drisaldi
Proceedings of the National Academy of Sciences, 2000
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Cross-linking cellular prion protein triggers neuronal apoptosis in vivo
Bruno Conti
Science, 2004
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Cytosolic Prion Protein Is Not Toxic and Protects against Bax-mediated Cell Death in Human Primary Neurons
Xavier Roucou
Journal of Biological Chemistry, 2003
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The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells
Valentina Bonetto
PloS one, 2012
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Prions - Some Physiological and Pathophysiological Aspects
Ivo Sirakov
2019
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Intracellular mechanisms mediating the neuronal death and astrogliosis induced by the prion protein fragment 106–126
Mario Salmona
International Journal of Developmental Neuroscience, 2000
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In vivo and in vitro neurotoxicity of the human prion protein (PrP) fragment P118-135 independently of PrP expression
isabelle sponne
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003
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Cytosolic Prion Protein Toxicity Is Independent of Cellular Prion Protein Expression and Prion Propagation
James Mastrianni
Journal of Virology, 2007
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Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells
Xavier Roucou
Journal of Neurochemistry, 2006
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A Mutant Prion Protein Sensitizes Neurons to Glutamate-Induced Excitotoxicity
Valentina Bonetto
Journal of Neuroscience, 2013
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Rapid ex vivo reverse genetics identifies the essential determinants of prion protein toxicity
Regina Reimann
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Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death
Robert B Petersen
Human Molecular Genetics, 2012
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Cell Type-Specific Neuroprotective Activity of Untranslocated Prion Protein
Gianluigi Forloni, Luana Fioriti
PLOS One, 2010
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Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death
Hubert Laude
Proceedings of the National Academy of Sciences, 2004
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A Neurotoxic Prion Protein Fragment Induces Rat Astroglial Proliferation and Hypertrophy
rinaldo doni
European Journal of Neuroscience
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Cellular prion protein is essential for oligomeric amyloid-β-induced neuronal cell death
George Perry
Human molecular genetics, 2012
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A Novel, Drug-based, Cellular Assay for the Activity of Neurotoxic Mutants of the Prion Protein
Valentina Bonetto
Journal of Biological Chemistry, 2010
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Exploring the mechanisms involved in prion degradation and spreading from cell-to-cell in neuronal cell models
ludovica marzo
2011
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Distinct spatial activation of intrinsic and extrinsic apoptosis pathways in natural scrapie: association with prion-related lesions
Luis Varona
Veterinary research
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Prion protein fragment PrP-(106-126) induces apoptosis via mitochondrial disruption in human neuronal SH-SY5Y cells
Deirdre Tobin
The Journal of biological chemistry, 2001
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Bcl-2 overexpression delays caspase-3 activation and rescues cerebellar degeneration in prion-deficient mice that overexpress amino-terminally truncated prion
Adriano Aguzzi
The FASEB Journal, 2007
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Prion protein on astrocytes or in extracellular fluid impedes neurodegeneration induced by truncated prion protein
Adriano Aguzzi
Experimental Neurology, 2009
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