Degenerative Cervical Myelopathy: Epidemiology, Genetics and Pathogenesis (original) (raw)

Spine, 2015

Abstract

ReviewObjective. To formally introduce 'Degenerative Cervical Myelopathy' as the overarching term to describe the various degenerative conditions of the cervical spine that cause myelopathy. Herein, the epidemiology, pathogenesis and genetics of conditions falling under this hypernym are carefully described. Non-traumatic, degenerative forms of cervical myelopathy represent the commonest cause of spinal cord impairment in adults and include Cervical Spondylotic Myelopathy (CSM), Ossification of the Posterior Longitudinal Ligament (OPLL), Ossification of the Ligamentum Flavum (OLF), and Degenerative Disc Disease (DDD). Unfortunately, there is neither a specific term nor specific diagnostic ICD-10 code to describe this collection of clinical entities. This has resulted in the inconsistent use of diagnostic terms when referring to patients with myelopathy due to degenerative disease of the cervical spine. Narrative review. The incidence and prevalence of myelopathy due to degen...

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