Ligand-Induced Endocytosis of Epidermal Growth Factor Receptors that are Defective in Binding Adaptor Proteins (original) (raw)

Endocytic Trafficking of the Epidermal Growth Factor Receptor in Transformed Cells

Brian Ceresa

cdn.intechopen.com

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An insertional mutant of epidermal growth factor receptor allows dissection of diverse receptor functions

Etta Livneh

1987

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Subsets of Epidermal Growth Factor Receptors during Activation and Endocytosis

David Moscatello

Journal of Biological Chemistry, 1997

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Epidermal Growth Factor Receptor Interaction with Clathrin Adaptors Is Mediated by the Tyr974-containing Internalization Motif

Johannes Boonstra

Journal of Biological Chemistry, 1996

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Cell surface insertion of exogenous epidermal growth factor receptors into receptor- mutant cells: demonstration of insertion in the absence of added fusogenic agents

Mark Pittenger

Proceedings of the National Academy of Sciences, 1982

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Mutations in the cytoplasmic domain of EGF receptor affect EGF binding and receptor internalization

Etta Livneh

The EMBO Journal, 1986

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Novel mechanism for regulation of epidermal growth factor receptor endocytosis revealed by protein kinase A inhibition

Alfonso Gonzalez

Molecular biology of the cell, 2002

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Spatial Regulation of Epidermal Growth Factor Receptor Signaling by Endocytosis

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International Journal of Molecular Sciences, 2012

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Polyubiquitination of the Epidermal Growth Factor Receptor Occurs at the Plasma Membrane upon Ligand-induced Activation

Espen Stang

Journal of Biological Chemistry, 2000

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Cross-linking of epidermal growth factor receptors in intact cells: detection of initial stages of receptor clustering and determination of molecular weight of high-affinity receptors

John Cidlowski

Biochemistry, 1986

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Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors

Paul M. P. Bergen Henegouwen

Journal of Cell Biology, 1989

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Ligand-induced internalization and increased cell calcium are mediated via distinct structural elements in the carboxyl terminus of the epidermal growth factor receptor

HANIS ALI

Journal of Biological Chemistry, 1991

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Activation of the Epidermal Growth Factor (EGF) Receptor Induces Formation of EGF Receptor- and Grb2-Containing Clathrin-Coated Pits

Espen Stang

Molecular and Cellular Biology, 2006

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Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells

Etta Livneh

Journal of Biological Chemistry, 1986

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Epidermal growth factor and transforming growth factor-alpha induce differential processing of the epidermal growth factor receptor

Ghanim Almahbobi

Biochemical and Biophysical Research Communications, 1990

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Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface

Michelle Palmer

2005

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Localization of a major receptor-binding domain for epidermal growth factor by affinity labeling

J. Schlessinger

Molecular and Cellular Biology, 1988

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The Membrane-proximal Intracellular Domain of the Epidermal Growth Factor Receptor Underlies Negative Cooperativity in Ligand Binding

Jennifer Obermann

Journal of Biological Chemistry, 2011

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Eps15 Is Recruited to the Plasma Membrane upon Epidermal Growth Factor Receptor Activation and Localizes to Components of the Endocytic Pathway during Receptor Internalization

Roberto Gradini

Molecular Biology of the Cell, 1999

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Signal Transduction by Epidermal Growth Factor Receptor

Annemarie Honegger

Cold Spring Harbor Symposia on Quantitative Biology, 1988

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Epidermal Growth Factor Receptor Phosphorylation Sites Ser991 and Tyr998 Are Implicated in the Regulation of Receptor Endocytosis and Phosphorylations at Ser1039 and Thr1041

Myron Toews, Debra Romberger

Molecular & Cellular Proteomics, 2009

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The Interaction of an Epidermal Growth Factor/Transforming Growth Factor alpha Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities

Sarah Puddicombe

Journal of Biological Chemistry, 1996

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Noncontiguous regions in the extracellular domain of EGF receptor define ligand-binding specificity

J. Schlessinger

Molecular Biology of the Cell, 1991

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The Interaction of an Epidermal Growth Factor/Transforming Growth Factor α Tail Chimera with the Human Epidermal Growth Factor Receptor Reveals Unexpected Complexities

S. M Puddicombe

Journal of Biological Chemistry, 1996

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Identification of a Determinant of Epidermal Growth Factor Receptor Ligand-Binding Specificity Using a Truncated, High-Affinity Form of the Ectodomain

Julie Rothacker

Biochemistry, 2001

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Structure−Function Studies of Ligand-Induced Epidermal Growth Factor Receptor Dimerization †

Sarah Puddicombe

Biochemistry, 1998

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Transforming Growth Factor Receptors Interact with AP2 by Direct Binding to 2 Subunit

Yoav Henis

2002

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A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor

Jana Ognjenovic

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Superagonistic behaviour of epidermal growth factor/transforming growth factor-alpha chimaeras: correlation with receptor routing after ligand-induced internalization

A. Lenferink

The Biochemical journal, 1997

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Domain deletion in the extracellular portion of the EGF-receptor reduces ligand binding and impairs cell surface expression

J. Schlessinger

Cell Regulation, 1990

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All ErbB Receptors Other Than the Epidermal Growth Factor Receptor Are Endocytosis Impaired

Maurizio Alimandi

Journal of Biological Chemistry, 1996

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Monoclonal antibody against epidermal growth factor receptor is internalized without stimulating receptor phosphorylation

Bruce Magun

Proceedings of the National Academy of Sciences, 1986

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Saturation of the Endocytic Pathway for the Transferrin Receptor Does Not Affect the Endocytosis of the Epidermal Growth Factor Receptor

Caroline Enns

Journal of Biological Chemistry, 1997

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