Gold nanostructures for OCT imaging of capillary flow (original) (raw)
2014, Biophotonics: Photonic Solutions for Better Health Care IV
In this paper, plasmon-resonant nanostructures, such as gold nanostars and their silica-coated composites, were used for enhancement of OCT image contrast of water flows in glass capillaries. The contrasting properties of the synthesized nanostars and nanocomposites with silica shell thickness of about 5 nm and 50 nm were compared in the framework of capillary stasis model. The most intensive signal was registered from the nanocomposites with the thickest silica shell. The nanocomposites were characterized by optical spectroscopy and electron microscopy. Aiming prospective application of the nanostructures for bioimaging, nontoxicity of nanostars and nanocomposites at least for concentrations lesser 3 mg/mL was shown by MTT assay.
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