Next generation stent coatings: convergence of biotechnology and nanotechnology (original) (raw)

The paper discusses advancements in next-generation stent coatings that integrate biotechnology and nanotechnology to improve coronary interventions. It highlights the transition from bare-metal and drug-eluting stents to novel coatings using nanocomposite polymers, focusing on enhancing endothelialization and reducing thrombosis. Key strategies include the use of biofunctionalized materials, layer-by-layer drug delivery systems, and targeted therapies via nanoparticles and gene therapy, aiming to address the limitations of previous stent designs.