FTY720 ameliorates oxazolone colitis in mice by directly affecting T helper type 2 functions
Heinfried Radeke
Molecular Immunology, 2007
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Sphingosine-1-Phosphate Receptor Agonism Impairs the Efficiency of the Local Immune Response by Altering Trafficking of Naive and Antigen-Activated CD4+ T Cells
Sam Koprak
The Journal of Immunology, 2003
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Inhibition of donor-derived T cells trafficking into target organs by FTY720 during acute graft-versus-host disease in small bowel transplantation
Masahiro Tanemura
Clinical and Experimental Immunology, 2006
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Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720
Margaret Morris
European Journal of Immunology, 2005
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and Antigen-Activated CD4 Response by Altering Trafficking of Naive Impairs the Efficiency of the Local Immune Sphingosine-1-Phosphate Receptor Agonism
Sam Koprak
2017
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Regulation of Donor T Cells in the Tolerant Rats to Graft-Versus-Host Disease by FTY720 Following Small Bowel Transplantation
Masahiro Tanemura
Transplantation Proceedings, 2006
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The Sphingosine-1-Phosphate Analogue FTY720 Impairs Mucosal Immunity and Clearance of the Enteric Pathogen Citrobacter rodentium
Fergus Shanahan
Infection and Immunity, 2012
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Sphingosine Kinase 2 Is Required for Modulation of Lymphocyte Traffic by FTY720
Yulius Setiady
Journal of Biological Chemistry, 2005
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FTY720 stimulates multidrug transporter– and cysteinyl leukotriene–dependent T cell chemotaxis to lymph nodes
Adam Yopp
Journal of Clinical Investigation, 2003
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Future targets for immune therapy in colitis?
Mogens Claesson
Endocrine, metabolic & immune disorders drug targets, 2008
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Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments
Bruno de Mattos
Mediators of Inflammation, 2015
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Preclinical evaluation of a new immunosuppressive agent, FTY720
Pablo Troncoso
Clinical Biochemistry, 1998
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Role of T-cell-associated lymphocyte function-associated antigen-1 in the pathogenesis of experimental colitis
Carla Brown
International Immunology, 2005
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Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720
James Milligan
Bioorganic & Medicinal Chemistry Letters, 2004
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4SC101, a novel immunosuppressive drug, inhibits IL17 and attenuates colitis in two murine models of inflammatory bowel disease
Leo Fitzpatrick
Inflammatory Bowel Diseases, 2010
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Toll-like receptor 6 stimulation promotes T-helper 1 and 17 responses in gastrointestinal-associated lymphoid tissue and modulates murine experimental colitis
A. Kraneveld
Mucosal Immunology, 2014
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Expression, Localization, and Functional Activity of TL1A, a Novel Th1-Polarizing Cytokine in Inflammatory Bowel Disease
Giorgos Bamias
The Journal of Immunology, 2003
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Review Article Inflammatory Bowel Disease: An Overview of Immune Mechanisms and Biological Treatments
Bruno de Mattos
Mediators of Inflammation
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TFF2 deficiency exacerbates weight loss and alters immune cell and cytokine profiles in DSS colitis, and this cannot be rescued by wild-type bone marrow
Anna Walduck, Treve Menheniott, Zinaida Dubeykovskaya, Louise Judd
Am J Physiol Gastrointest Liver Physiol, 2015
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Vasoactive intestinal peptide and regulatory T-cell induction: a new mechanism and therapeutic potential for immune homeostasis
Mario Delgado
Trends in Molecular Medecine, 2007
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Biological Treatments in Inflammatory Bowel Disease: A Complex Mix of Mechanisms and Actions
Raquel Abalo Delgado
Biologics, 2021
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Immunosuppressive activity of a new pteridine derivative (4AZA1378) alleviates severity of TNBS-induced colitis in mice
Ilse Sienaert
Clinical Immunology, 2007
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Effect of α4β7 blockade on intestinal lymphocyte subsets and lymphoid tissue development
Manreet kaur
Inflammatory Bowel Diseases, 2010
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II. The yin and yang of T cells in intestinal inflammation: pathogenic and protective roles in a mouse colitis model
Mitchell Kronenberg
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1999
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Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720
Diana Mechtcheriakova
Blood, 2006
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Prevention of experimental colitis by parenteral administration of a pathogen-derived immunomodulatory molecule
Dr Padraic Dunne
Gut, 2007
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CD73 Is Critical for the Resolution of Murine Colonic Inflammation
Agnieszka Czopik
Journal of Biomedicine and Biotechnology, 2012
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Prevents Th2 Cell-Type Colitis Lymphotoxin {beta} Receptor-Ig Elimination of Colonic Patches with
Paul Rennert
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FTY720 ameliorates experimental autoimmune neuritis by inhibition of lymphocyte and monocyte infiltration into peripheral nerves
Hermann Schluesener
Experimental Neurology, 2008
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