Analysis of case-cohort data: A comparison of different methods (original) (raw)

Profile image of Mark RoestMark Roest

2007, Journal of Clinical Epidemiology

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6 pages

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Objective: The case-cohort design combines the advantages of a prospective cohort study and the efficiency of a caseecontrol design. Usually a Cox proportional-hazards model is used for the analyses. However, adaptation of the model is necessary because of the sampling. We compared three methods that were proposed in the literature, which differ in weighting of study subjects: Prentice's, Barlow's, and Self and Prentice's method.