Molecular signature of retinoic acid treatment in acute promyelocytic leukemia (original) (raw)
RARα2 and PML-RAR similarities in the control of basal and retinoic acid induced myeloid maturation of acute myeloid leukemia cells
Gabriela Paroni
Oncotarget, 2016
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PML/RARα Targets Promoter Regions Containing PU.1 Consensus and RARE Half Sites in Acute Promyelocytic Leukemia
Kan-kan Wang
Cancer Cell, 2010
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Pro-proliferative function of the long isoform of PML-RARα involved in acute promyelocytic leukemia
Ananda Roy
Oncogene, 2006
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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML
Murty V Vundavalli
Cell, 1991
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Chromosomal Translocation t(l5;17) in Human Acute Promyelocytic Leukemia Fuses RARa with a Novel Putative Transcription Factor, PML
Murty V Vundavalli
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PML protein expression in hematopoietic and acute promyelocytic leukemia cells
marcel koken
Blood, 1993
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Formation of PML/RARα high molecular weight nuclear complexes through the PML coiled-coil region is essential for the PML/RARα-mediated retinoic acid response
Mirco Fanelli
Oncogene, 1999
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Opposite Effects of the Acute Promyelocytic Leukemia PML-Retinoic Acid Receptor α (RARα) and PLZF-RARα Fusion Proteins on Retinoic Acid Signalling
ugo testa
Molecular and Cellular Biology, 1997
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PML-RAR induces promyelocytic leukemias with high efficiency following retroviral gene transfer into purified murine hematopoietic progenitors
Alberto Gobbi
2002
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Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding …
P. Ferrucci
The EMBO …, 1996
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Targeting the PML/RARα translocation product triggers apoptosis in promyelocytic leukemia cells
Garry Takle
Oncogene, 1998
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Retinoid-Induced Differentiation of Acute Promyelocytic Leukemia Involves PML-RARa - Mediated Increase of Type I1 Transglutaminase
Anton Jetten
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Opposite effects of the acute promyelocytic leukemia PML-retinoic acid receptor alpha (RAR alpha) and PLZF-RAR alpha fusion proteins on retinoic acid signalling
Francesco Grignani
Molecular and cellular biology, 1997
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Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region
Toshihiko Imamura
Blood cancer journal, 2014
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Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia
Klaus Laczika
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Chromatin modifications induced by PML-RAR repress critical targets in leukemogenesis as analyzed by ChIP-Chip
Michael McClelland
Blood, 2008
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Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia
Guilherme Queiroz dos Santos
Journal of Experimental Medicine, 2013
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Retinoic Acid Receptor Fusion to PML Affects Its Transcriptional and Chromatin-Remodeling Properties
S. Segalla
Molecular and Cellular Biology, 2003
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pml/RAR alpha protein leukemia cell line NB4 is associated with altered expression of the Occurrence of resistance to retinoic acid in the acute promyelocytic
Francesco Grignani
2010
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Effects on differentiation by the promyelocytic leukemia PML/RARalpha protein depend on the fusion of the PML protein dimerization and RARalpha DNA binding domains
Francesco Grignani
The EMBO journal, 1996
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Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia
Vania Gelmetti
Blood, 2007
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Variant-type PML-RAR fusion transcript in acute promyelocytic leukemia: Use of a cryptic coding sequence from intron 2 of the RAR gene and identification of a new clinical subtype resistant to retinoic acid therapy
Samuel Waxman
Proceedings of The National Academy of Sciences, 2002
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Acute leukemia with promyelocytic features in PML/RAR transgenic mice
Carla Tribioli
Proceedings of the National Academy of Sciences, 1997
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PML, a growth suppressor disrupted in acute promyelocytic leukemia
Zhao Mu
Molecular and Cellular Biology, 1994
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Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARα Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia
Mats Söderström
Blood, 1998
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Genome-wide functions of PML-RARα in acute promyelocytic leukaemia
Colin Logie
British journal of cancer, 2011
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