EXPERIMENTAL INFECTION OF THE UPPER GENITAL TRACT OF FEMALE GRIVET MONKEYS WITH MYCOPLASMA FERMENTANS (original) (raw)

2% or less of the mycoplasma flora of the lower urogenital tract of man Mirdh, Nilsson and Bjelle, 1973). It has been isolated on one occasion from an inflamed uterine tube , but the possible significance of this species as an aetiological agent in gynaecological inflammatory disease requires further study. The very frequent association of M . fermentans with rheumatoid arthritis reported by Williams, Brostoff and Roitt (1 970) remains largely unconfirmed, although the organism has been isolated from the synovial fluid of patients with rheumatoid and non-rheumatoid arthritis . The toxic effect of M . fermentans membrane fractions, when inoculated intraperitoneally in high concentrations into mice , provides another impetus for studying the potential pathogencity of this organism.