Histochemical, biochemical, and ultrastructural analyses of single human muscle fibers, with special reference to the C-fiber population (original) (raw)

Human skeletal muscle is composed of four basic fiber types differentiated by histochemical methods, particularly focusing on the C-fiber population, which exhibits distinct oxidative capacities between the various fiber types. This study performs histochemical, biochemical, and ultrastructural analyses of single human muscle fibers, revealing complexities in C-fiber characteristics and their potential roles within the continuum of muscle fiber types. The findings suggest a need to reconsider the classification and functionality of these fibers as they may represent transitional forms or distinct populations adapted for specific physiological roles.