An integrated transcriptome and expressed variant analysis of sepsis survival and death (original) (raw)

Profile image of J C VAN VELKINBURGH J C VAN VELKINBURGH Profile image of Raymond Langley Raymond Langley

2014, Genome Medicine

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15 pages

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Background: Sepsis, a leading cause of morbidity and mortality, is not a homogeneous disease but rather a syndrome encompassing many heterogeneous pathophysiologies. Patient factors including genetics predispose to poor outcomes, though current clinical characterizations fail to identify those at greatest risk of progression and mortality.