Activation of primary sensory neurons by the topical application of capsaicin on the epidermis of a re-innervated organotypic human skin model (original) (raw)

Intradermal Injection of Capsaicin in Humans Produces Degeneration and Subsequent Reinnervation of Epidermal Nerve Fibers: Correlation with Sensory Function

Donald Simone

The Journal of Neuroscience, 1998

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Capsaicin-sensitive afferents are involved in signalling transneuronal effects between cutaneous sensory nerves

Emma O'Neill

Neuroscience, 1999

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Encoding of burning pain from capsaicin-treated human skin in two categories of unmyelinated nerve fibres

Hermann Handwerker

Brain, 2000

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New neurophysiological findings on skin receptors or intradermal nerve endings after repetitive capsaicin application

Maria Pia Foschini

Journal of the Peripheral Nervous System, 2004

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Mechanisms involved in an increment of multimodal excitability of medullary and upper cervical dorsal horn neurons following cutaneous capsaicin treatment

Koichi Iwata

Molecular Pain, 2008

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The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres

Hermann Handwerker

Brain Research, 1983

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Substance P content of the skin, neurogenic inflammation and numbers of C-fibres following capsaicin application to a cutaneous nerve in the rabbit

jumah Shakhanbeh

Neuroscience, 1988

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Involvement of capsaicin-sensitive afferent nerve fibres in serotonin-induced plasma extravasation and vasodilatation in rat skin

Zeinab Khalil

Neuroscience Letters, 1989

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Evidence for two independent modes of activation of the ‘efferent’ function of capsaicin-sensitive nerves

Riccardo Patacchini

European Journal of Pharmacology, 1988

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Increased capsaicin receptor TRPV1 in skin nerve fibres and related vanilloid receptors TRPV3 and TRPV4 in keratinocytes in human breast pain

Elaine Wan

BMC Women's Health, 2005

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A Novel In Vitro Assay Using Human iPSC-Derived Sensory Neurons to Evaluate the Effects of External Chemicals on Neuronal Morphology: Possible Implications in the Prediction of Abnormal Skin Sensation

Kenji Takamori

International Journal of Molecular Sciences, 2021

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Octreotide inhibits capsaicin-induced activation of C and Aδ afferent fibres in rat hairy skin in vivo

Dongyuan Cao

Clinical and Experimental Pharmacology and Physiology, 2011

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Physiology The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres

Hermann Handwerker

Pain, 1984

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Excitation of central and peripheral terminals of primary afferent neurons by capsaicin In vivo

Gábor Pethô

Life Sciences, 1995

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Capsaicin-sensitive cutaneous primary afferents convey electrically induced itch in humans

Antoinette van Laarhoven

Neuroscience Letters, 2018

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Sensory receptors in mammalian skin in an in vitro preparation

Peter Reeh

Neuroscience Letters, 1986

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Long‐Term Effects of Neonatal Capsaicin Treatment on Intraepidermal Nerve Fibers and Keratinocyte Proliferation In Rat Glabrous Skin

Eduardo Martínez-Martínez

… Record: Advances in …

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The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers

Nathalie Van Acker, Maarten Timmers, Theo Meert, Ravikiran Shenoy

Clinical Neurophysiology, 2010

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Expression of capsaicin receptor immunoreactivity in human peripheral nervous system and in painful neuropathies

Mauro Manconi

Journal of the Peripheral Nervous System, 2006

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A novel human volunteer pain model using contact heat evoked potentials (CHEP) following topical skin application of transient receptor potential agonists capsaicin, menthol and cinnamaldehyde

Ravikiran Shenoy

Journal of Clinical Neuroscience, 2011

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Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro

Peter Reeh

Experimental Brain Research, 2009

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Behavioral and electrophysiological study of cutaneous trigeminal nerves in axolotls. I. Normal innervation and reinnervation following nerve section

Gulnazi Gurtskaia

Developmental Brain Research, 1981

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Perineural Capsaicin Treatment Inhibits Collateral Sprouting of Intact Cutaneous Nociceptive Afferents

Gábor Jancsó

Biomedicines

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Influence of inflammation or disconnection from peripheral target tissue on the capsaicin sensitivity of rat dorsal root ganglion sensory neurones

Janet Winter

Neuroscience Letters, 1996

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In vitro interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue-engineered reconstructed skin

Heather Durham

Experimental Dermatology, 2008

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Neurogenic flare responses following topical application of capsaicin in humans

Robert Helme

Annals of Neurology, 1985

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Phenotyping sensory nerve endings in vitro in the mouse

Katharina Zimmermann

Nature Protocols, 2009

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The effect of topical capsaicin-induced sensitization on heat-evoked cutaneous vasomotor responses

LARISSA GOLLA DA SILVA

International journal of physiology, pathophysiology and pharmacology, 2013

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Low intensity intra-epidermal electrical stimulation can activate A [delta]-nociceptors selectively

Leon Plaghki

Pain, 2010

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