Invasive aspergillosis and allogeneic hematopoietic stem cell transplantation in children: a 15-year experience (original) (raw)

Invasive aspergillosis (IA) continues to be a leading cause of infection-related mortality among children post-allogeneic hematopoietic stem cell transplantation (AHSCT). This retrospective study reviews 15 years of medical data, identifying ten cases of IA in a cohort of AHSCT patients, revealing a 2.7% incidence and a concerning 90% mortality rate. Outcomes suggest that while AHSCT can be considered in children with prior IA, there is an urgent need for improved antifungal strategies to manage high-risk patients effectively, particularly in light of emerging therapies.