Endovascular Treatment of Cerebral Aneurysms (original) (raw)
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Endovascular Treatment of Cerebral Aneurysms at a Low-Volume Institution: A Viable Alternative?
Journal of Neuroimaging, 2012
The advances of the endovascular techniques observed in the past two decades has made this surgical alternative, previously recommended only for aneurysms with no indication to be treated by conventional surgical technique (clipping), into a first choice approach for a large number of cerebral aneurysms in some services 1-3 . One of the main advances in these techniques was the advent of detachable plat-inum coils termed Guglielmi detachable coils (GDC). The development of coils with a better capacity to conform to aneurysms, quicker and safer detachable mechanisms and the use of bioactive materials in addition to coils are responsible for the higher rate currently obtained in aneurysm occlusion 4 . The development of the remodeling techniques, the use of intracranial stents and of liquid embolic ma-ABSTRACT -Objective: To present the results of cerebral aneurysms treated by endovascular technique. Method: Retrospective analysis of patient files of Hospital Geral de Fortaleza, Brazil. Results: We report the results of 163 cerebral aneurysms treated by endovascular techniques from January 2002 to October 2005. Patients with ruptured aneurysms (87.2%), according to Hunt-Hess scale were: 33.7% HH I, 28.4% HH II, 24.1% HH III, 13.8% HH IV. The Fisher scale grade IV was the most common (39.7%). Remodeling, coil embolization, arterial occlusion and histoacryl embolization were the techniques employed. Effective occlusion was achieved in 87.7%, partial occlusion in 5.3% and non-effective occlusion in 7.0% of the patients. Glasgow outcome scale results were: 76.3% GOS 5, 5.0% GOS 4, 5.8% GOS 3, 1.4% GOS 2 and 11.5% GOS 1. Conclusion: Endovascular treatment seems to be feasible within Brazilian public health system, with results as good as those obtained in larger international centers.
Endovascular treatment of cerebral aneurysms: a retrospective study of 163 embolized aneurysms
Arquivos De Neuro-psiquiatria, 2007
OBJECTIVE: To present the results of cerebral aneurysms treated by endovascular technique. METHOD: Retrospective analysis of patient files of Hospital Geral de Fortaleza, Brazil. RESULTS: We report the results of 163 cerebral aneurysms treated by endovascular techniques from January 2002 to October 2005. Patients with ruptured aneurysms (87.2%), according to Hunt-Hess scale were: 33.7% HH I, 28.4% HH II, 24.1% HH III, 13.8% HH IV. The Fisher scale grade IV was the most common (39.7%). Remodeling, coil embolization, arterial occlusion and histoacryl embolization were the techniques employed. Effective occlusion was achieved in 87.7%, partial occlusion in 5.3% and non-effective occlusion in 7.0% of the patients. Glasgow outcome scale results were: 76.3% GOS 5, 5.0% GOS 4, 5.8% GOS 3, 1.4% GOS 2 and 11.5% GOS 1. CONCLUSION: Endovascular treatment seems to be feasible within Brazilian public health system, with results as good as those obtained in larger international centers.
2017
Objective: Correlate the middle cerebral artery bifurcation aneurysm morphology with the pre-operative and intra-operative risk of rupture. Methods: Forty patients with 46 middle cerebral artery bifurcation aneurysms were treated microsurgically by the same surgeon. Aneurysms were classified according to shape and the Fisher test was applied to analyze the effect of morphology on the pre-operative and intra-operative rupture. Results: Pre-operative and intra-operative ruptures were observed in 8/46 patients (17.4%) and 14/46 patients (30.4%) respectively. Thirty-two cases (69.6%) had no symptoms postoperatively, modified Rankin score (MRS) of 0; 6.5% had MRS of 1 (no significant disability); 13% had MRS of 2 (slight disability); 4.3% had moderately severe disability (MRS of 4); and there were 3 deaths (6.5%) post-operatively. The morphology was not directly related to the rupture rate. Conclusion: In general, ruptures are not affected by the morphology or the studied variables. Larg...
JBNC - JORNAL BRASILEIRO DE NEUROCIRURGIA
Introduction: Intracerebral Aneurysms are important causes of morbidity and mortality, with mortality rate of up to 50%. Endovascular coiling was introduced as an alternative to surgical clipping, and has shown better results with a reduction in morbidity and mortality risk of 6-9%. Objective: To characterize the two types of treatment for intracerebral aneurysms within Brazilian scenario, and to compare the results with the international literature. Methods: An analytic observational study using data from the SIH / DATASUS (National Health Information System) in the period of 2010-2015. Results: The total number of hospitalizations decreased, with a 38.3% decrease in clipping and 18.4% in embolizations. The mean value of embolization was significantly higher, however, presenting a downward trend (R$ 22,011.37 in 2010 to R$ 15,607.18 in 2015), while the value of microsurgery increased (R$ 7,022.31 to R$ 8,645.28, respectively). Microsurgery was a risk factor for death (p-value <0...
Tratamiento de aneurismas de arteria cerebral media: estudio comparativo y algoritmo de tratamiento
Cirugía y Cirujanos
Objectives: We aimed to compare outcomes of patients with middle cerebral artery (MCA) aneurysms treated by either microsurgical clipping or endovascular therapy and provide a treatment algorithm based on available evidence. Materials and methods: We performed a retrospective analysis of 77 patients with 95 MCA aneurysms. Demographic, clinical, and aneurysm morphological variables were collected. Patients were divided into two groups depending on the received treatment. Clinical and radiological outcomes were collected at the end of a 1-year follow-up period and compared between both treatment groups. Results: Mean age was 51.4 years. Fifty patients (65%) underwent microsurgical clipping and 27 (35%) were treated by endovascular therapy. Fifty-four patients (70%) presented with subarachnoid hemorrhage, while 23 (30%) were treated for unruptured aneurysms. Patients with subarachnoid hemorrhage were more frequently treated by microsurgical clipping than patients with unruptured aneurysms. Clinical outcomes, including functional status, were similar between treatment groups after 1-year follow-up even when adjusting for clinical presentation. Residual aneurysms were found less frequently in the microsurgical group (OR = 0.09; p < 0.001). Conclusions: In patients with MCA aneurysms, clinical outcomes at 1 year are similar between microsurgical clipping and endovascular therapy. However, microsurgery is associated with a lower risk of residual aneurysms.
World Neurosurgery, 2018
The purpose of this study was to evaluate the frequency and causes of thromboembolic events associated with endovascular embolization of asymptomatic aneurysms. Correlations between radiological findings (aneurysm size, localization, embolization time, number of coils used, as well as patient age) were evaluated with the occurrence of thromboembolic events and clinical findings. METHODS: Sixty-eight patients treated for unruptured intracranial aneurysms (mean age, 49 yr) were evaluated. Hyperintense lesions on diffusion weighted imaging were analyzed in 50 patients. Aneurysm size was 3 to 15 mm. RESULTS: Complete occlusion of the aneurysms was achieved in 55 of 68 (82%). One patient had a transient paresis. There was one infarction and one aneurysm rupture during the procedure with no consecutive neurological symptoms. We found new hyperintense lesions in 21 of 50 (42%) diffusion weighted imaging studies. In 43% of these, there was only one lesion smaller than 2 mm. In 33%, there was more than one lesion less than 2 mm; in 19%, we found a lesion of 2 to 10 mm in size. In one case, a lesion greater than 10 mm occurred. There was no correlation between aneurysm location and the occurrence of lesions or among the number of coils used, the size of the aneurysm, patient age, or embolization time. Mortality rate was 0%, morbidity 4.0%. If the 18 aneurysms where no diffusion weighted imaging was obtained are included, morbidity is 2.9%. CONCLUSION: The high rate of thromboembolic events suggests that heparin is not sufficient to prevent ischemic lesions. An antiplatelet therapy, started before or during intervention, might diminish thrombus formation.
Outcome of 337 intracranial aneurysms patients operated in a public hospital
Arquivos de Neuro-Psiquiatria, 1998
Many recent series of surgery for intracranial aneurysms have been based on experience of developed countries with great resources and a state of art health care. The purpose of the current study is to correlate the outcome of patients operated for intracranial aneurysms. reported from intensive high technology neurosurgical centers with the results of low technology, environment, where we practice. Between January 1986 and December 1996, 337 patients with intracranial aneurysms were operated on at the Servidores do Estado Hospital. We retrospectively reviewed the medical and radiologic records and compared the outcome of this group with other series derived from developed countries. The overall mortality of this series was 6.9%. Of the 313 good grades surgical patients, the mortality was 4.7% and the sucessfull results were obtained in 88.8% individuals. We conclude that patients harboring intracranial aneurysms can be satisfactory handled in less developed nations, if a meticulous intraoperative technique is employed, even though sophisticated technology and equipments are not available.
World neurosurgery, 2018
Nowadays, the use of microsurgery for clipping aneurysms has decreased considerably. To demonstrate the safety and effectiveness of surgical treatment of intracranial aneurysms even in less developed countries. Retrospective review of the medical records of 320 patients with 416 aneurysms treated with microsurgical clipping from 2008 to 2016 in a single neurosurgical center in Brazil. This study evaluated postoperative outcome, using the modified Rankin Scale (mRS) on hospital discharge, treatment efficacy, assessed by digital subtraction angiography (DSA) performed postoperatively, and mortality. Among 320 patients with aneurysms, 228 patients presented with ruptured aneurysms and 92 patients with unruptured aneurysms. Overall, 81 (26,3%) presented poor outcome (mRs>2) while 227 (73,4%) showed good outcome. The presence of a ruptured aneurysm was a statistically significant factor for poor outcome (p<0,001) and mortality (p<0,015). Giant and large aneurysms were also assoc...