Difluoromethylbenzoxazole Pyrimidine Thioether Derivatives: A Novel Class of Potent Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors (original) (raw)
Synthesis, Biological Activity, and Crystal Structure of Potent Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase That Retain Activity against Mutant Forms of the Enzyme â€
Kalyan Das
Journal of Medicinal Chemistry, 2007
View PDFchevron_right
Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties
Tiziana Ginex
View PDFchevron_right
2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors
Anna Carbone
Antiviral Research, 2004
View PDFchevron_right
Design, synthesis, and structure–activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents
Laura De Luca
Bioorganic & Medicinal Chemistry, 2009
View PDFchevron_right
Discovery of piperidine-substituted thiazolo[5,4-d]pyrimidine derivatives as potent and orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitors
Peng Zhan
Communications Chemistry, 2019
View PDFchevron_right
Arylazolylthioacetanilide. Part 11: Design, Synthesis and Biological Evaluation of 1,2,4-triazole Thioacetanilide Derivatives as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors
Xinyong Liu
Medicinal Chemistry, 2013
View PDFchevron_right
1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors
Xinyong Liu
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Design, Synthesis, and Evaluation of Thiophene[3,2-d]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles
Peng Zhan
Journal of medicinal chemistry, 2016
View PDFchevron_right
1BENZOYL2-(2-NITROPHENYL)-1H-BENZIMIDAZOLE DERIVATIVES: A NOVEL APPROACH TO THE DEVELOPMENT OF NEW HIV1 REVERSE TRANSCRIPTASE INHIBITORS
Luis Angel Gonzalez
Journal of The Chilean Chemical Society, 2007
View PDFchevron_right
Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors
Xinyong Liu
European Journal of Medicinal Chemistry, 2009
View PDFchevron_right
Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses
Georgia McGaughey
Journal of Medicinal Chemistry, 2008
View PDFchevron_right
Structure-Based Design, Synthesis, and Biological Evaluation of Conformationally Restricted Novel 2-Alkylthio-6-[1-(2,6-difluorophenyl)alkyl]- 3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase
Gianluca SBARDELLA
Journal of Medicinal Chemistry, 2001
View PDFchevron_right
Synthesis and evaluation of oligo-1,3-thiazolecarboxamide derivatives as HIV1 reverse transcriptase inhibitors
Olga Zakharova
Bioorganic & Medicinal Chemistry, 2000
View PDFchevron_right
Novel Thiazolidin-4-ones as Potential Non-nucleoside Inhibitors of HIV-1 Reverse Transcriptase
Athina Geronikaki
Molecules, 2019
View PDFchevron_right
Anti-HIV agents: design and discovery of new potent RT inhibitors
Laura Luca
Farmaco, 2003
View PDFchevron_right
Recent Advances in the Research of 2,3-Diaryl-1,3-thiazolidin-4-one Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors
Xinyong Liu
Current Medicinal Chemistry, 2012
View PDFchevron_right
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV1 reverse transcriptase inhibitors
Laura De Luca
Bioorganic & Medicinal Chemistry, 2010
View PDFchevron_right
Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase
John Young
Virology Journal, 2012
View PDFchevron_right
Rational design and synthesis of novel thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors
Reshu Saxena
Bioorganic & Medicinal Chemistry, 2014
View PDFchevron_right
Synthesis and Biological Evaluation of 2-Thioxopyrimidin-4(1H)-one Derivatives as Potential Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors
Nagy Khalifa
International Journal of Molecular Sciences, 2014
View PDFchevron_right
N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Michael Wang
Bioorganic & Medicinal Chemistry Letters, 2010
View PDFchevron_right
Synthesis and HIV1 inhibition of novel benzimidazole derivatives
Adil Khan
Bioorganic & Medicinal Chemistry Letters, 1995
View PDFchevron_right
N1-Alkyl pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase
Jianhong Wang
Bioorganic & Medicinal Chemistry Letters, 2010
View PDFchevron_right
Structural basis for potent and broad inhibition of HIV-1 RT by thiophene[3,2-d]pyrimidine non-nucleoside inhibitors
Zachary Smithline
View PDFchevron_right
The PETT series, a new class of potent nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase
T. Unge
Antimicrobial Agents and Chemotherapy, 1995
View PDFchevron_right
Benzoyl-2-(2-Nitrophenyl)-1H-Benzimidazole Derivatives: A Novel Approach To The Development Of New HIV-1 Reverse Transcriptase Inhibitors
Angel Gonzalez
Journal of the Chilean Chemical Society, 2007
View PDFchevron_right
Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities
Nicolino Pala
International journal of molecular sciences, 2016
View PDFchevron_right
5Alkyl2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3 H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family
Gianluca SBARDELLA
Bioorganic & Medicinal Chemistry, 2005
View PDFchevron_right