Maturing Pyogenic Granuloma – A report of two cases (original) (raw)

Pyogenic granuloma. A case report

Journal of the American Podiatric Medical Association, 1973

Pyogenic granuloma is a fast growing reactive proliferation of endothelial cells commonly on the gingiva and usually in response to chronic irritation. It is a polypoid form of capillary hemangioma on the skin & mucosal surfaces. This paper present of case of pyogenic granuloma found on the cheek adjacent to retromolar region.

Self-progressing Granulomatous Growth in Pediatric Patients: Pyogenic Granuloma?

International Journal of Preventive and Clinical Dental Research, 2016

Fibrous overgrowths of soft tissues in oral cavity are relatively common and may be quite challenging to diagnose. Pyogenic granuloma is one such entity which occurs commonly in response to chronic local irritation, e.g., calculus, fractured tooth or restoration, foreign materials, etc. It occurs predominantly in females, probably due to the action of female hormones. These lesions are generally asymptomatic and are reported only due to difficulty in mastication. Treatment includes complete excision of the lesion along with the removal of causative factor. This paper describes a case of pyogenic granuloma in a ten-anda-half-year-old girl, presenting with a single, irregular, reddish maxillary gingival swelling in relation to mobile 63.

Pyogenic granuloma-a 19 months follow up case report

Update Dental College Journal, 2015

Pyogenic granuloma is one of the inflammatory hyperplasia seen in the oral cavity. This term is a misnomer because the lesion is unrelated to infection and in reality arises in response to various stimuli such as low-grade local irritation, traumatic injury or hormonal factors. Clinically, oral pyogenic granuloma is a smooth or lobulated exophytic lesion manifesting as small, red erythematous papules on a pedunculated or sometimes sessile base, which is usually hemorrhagic. The surface ranges from pink to red to purple, depending on the age of the lesion. Because of the high frequency of pyogenic granuloma in the oral cavity, especially during pregnancy, and necessity for proper diagnosis and treatment, a complete information and investigations about this lesion, in addition its treatment is presented. The study emphasizes the clinical follow-up after the treatment of patients that present pyogenic granuloma. Follow-up over 19 months of surgical procedures demonstrated the maintenance of a periodontal health decreases the chances of recurrence.

"Pyogenic Granuloma"-Is the Name Justified?: A Case Series

https://ijshr.com/IJSHR\_Vol.5\_Issue.3\_July2020/IJSHR\_Abstract.0057.html, 2020

Pyogenic granuloma is a non-neoplastic, tumor like growth (inflammatory hyperplasia) affecting skin and oral mucosa. These lesions appear in the mouth due to physical trauma, hormonal factors etc. They attain various clinical and histological forms in the oral cavity. This article presents four case reports of pyogenic granuloma of the gingiva including their management, histopathological features and highlight why the term "pyogenic granuloma" is a misnomer.

A Case Report: Aggressive Pyogenic Granuloma

Dental Journal of Advance Studies, 2019

Soft-tissue growths of the oral cavity offer a diagnostic dilemma because of the pathologic processes produced by such lesions. Pyogenic granuloma (PG) is one such soft-tissue swelling that originates from the reactive inflammatory course in which an exuberant fibrovascular expansile growth of the connective tissue of the skin or mucous membrane occurs. This case report documents a rare case in which the size and the site of the PG were different from the usual. The treatment included the extraction of the involved tooth in addition with the surgical removal of the lesion. The present case report demonstrates that the treatment of choice varies according to individual case after the adequate analysis of clinical and radiographic findings and should be managed appropriately to minimize further reoccurrence of the lesion and postsurgical complications.

Uncommon location of pyogenic granuloma in a child – case report and mini-review

Archives of the Balkan Medical Union, 2020

Localisation peu fréquente du granulome pyogène dans l'enfance-cas clinique et mini-revue Introduction. Le granulome pyogène (GP) est une hyperplasie inflammatoire vasculaire qui affecte la peau et la muqueuse buccale, souvent associée à une irritation ou un traumatisme local, ou à une grossesse. La localisation intra-orale affecte généralement la gencive, mais l'aspect tumoral peut être trompeur, en particulier dans les localisations extra-gingivales. Une évaluation et un diagnostic approfondis sont donc importants pour garantir un traitement approprié. Présentation du cas. Nous présentons le cas d'un garçon de 12 ans qui est venu pour une consultation concernant la tumeur croissante et saignante de sa muqueuse de la lèvre inférieure. La tumeur a été étiquetée comme « hémangiome ». Elle se développait depuis plusieurs semaines et avait été associée à un traumatisme muqueux mineur mais répété. Bien que la localisation anatomique ne soit pas courante, les antécédents du patient suggéraient un diagnostic de GP. Après une consultation dermatologique qui proposait un diagnostic différentiel avec le papillome buccal, une échographie des tissus mous avait soutenu le diagnostic clinique. La tumeur a été excisée chirurgicalement et ABSTRACT Introduction. Pyogenic granuloma (PG) is a vascular inflammatory hyperplasia involving the skin and oral mucosa, often associated with local irritation or trauma, or with pregnancy. Intraoral location usually affects the gingiva, but tumoral aspect can be misleading, especially in extra-gingival locations. A thorough assessment and diagnosis are therefore important for ensuring the proper treatment. Case presentation. We report the case of a 12-year-old boy who presented for a growing and bleeding tumour of his lower lip mucosa. The tumour was labeled as "hemangioma". It was growing for several weeks and associated with minor, but repeated mucosal trauma. Although the anatomic location was not common, the patient history suggested a diagnosis of PG. After a dermatologic assessment, which proposed a differential diagnosis with oral papilloma, a soft tissue ultrasound sustained the clinical diagnosis. The tumour was surgically excised and the defect was closed directly with absorbable sutures. Three weeks later the mucosa had a healthy appearance, without signs of impaired healing or tumour recurrence. The histopathological exam confirmed the clinical diagnosis. Conclusions. There are several types of soft tissue solid or vascular tumours that can be mislabeled and

Pyogenic granuloma: Report of two cases with review of literature

Journal of Periodontology & Implant Dentistry

Pyogenic granuloma (PG) is a reactive inflammatory hyperplastic oral lesion in response to local irritants. It is the most commonly occurring and a well-known oral lesion by oral physicians that most commonly affects gingiva, followed by lips, buccal mucosa, palate and tongue. "Pyogenic granuloma" term itself is a misnomer. This article presents a report of 2 cases of pyogenic granuloma of the gingiva and their management with a review of literature and also discusses why the term "pyogenic granuloma" is a misnomer.

Pyogenic Granuloma—a case report and review of literature

international journal of stomatology & occlusion medicine, 2011

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Pyogenic granuloma - Report of three cases in rare sites

Bangladesh Journal of Medical Science, 2013

Pyogenic granuloma is a benign, localized mass of exuberant granulation tissue produced in response to various stimuli. It is inflammatory hyperplasia of oral cavity commonly seen on gingival area and rarely on other parts of oral cavity such as lips, tongue, palate and buccal mucosa. It is seen predominantly in 2 nd to 3 rd decade of life in young females. Clinically manifesting as small red erythematous exophytic lesion, it must be biopsied to rule out other serious conditions. This article aims to present three cases of extra gingival pyogenic granulomas occurring in rare sites such as buccal mucosa, anterior hard palate and alveolar mucosa of completely edentulous ridge in maxilla. Pyogenic granuloma on buccal mucosa and anterior hard palate were seen in female patients with age of 40 years and 34 years respectively and pyogenic granuloma on alveolar mucosa of edentulous ridge in maxilla was noted in 70 years old male patient. Surgical excision was performed for all the lesion and follow up of one year did not show any recurrence. Please add little description of patient + treatment + followup results.

Recurrent pyogenic granuloma: an update

Given the fierce controversy about the nature of pyogenic granulomas, starting with its unfitting name and ending up with its ideal treatment modality, this paper tries to numerically identify some predisposing factors of recurrence. Methods: The literature was initially reviewed and a total of twenty recurrent cases of pyogenic granuloma were contrasted, on one hand, to their initial appearance. On the other hand, all are contrasted to a similar number of normal mucosa using three histochemical stains: Alcian blue, periodic acid-Schiff and Masson's trichrome. Results: For all recurrent lesions, all specimens showed myxoid structure histologically even if their initial appearance had possessed a sparse myxoid structure. The age of recurrence has been correlated to the histochemical findings. For the Alcian Blue stain (AB), the value of t-test was 3.808840. The pertaining value of P was 0.000593. The result was significant at P ≤0.05. For the PAS stain, the value of t-test was 3.640327. The value of P was 0.000871. The result was significant at P ≤0.05. In Masson's trichrome staining, the value of t-test was 3.100816. The value of P was 0.002942. The result was significant at P ≤0.05. Accordingly, all stains showed significant difference in fibrous content in the initial and recurrent lesions. Conversely, the count of both endothelial vessels and inflammatory infiltrates in the recurrent lesions were significantly lower than the primary precursors. Conclusions: Given that collagen fibers are continually degraded and resynthesized while proteolytic degradation occur outside the cells through the activity of enzymes called matrix metalloproteinases (MMPs), it is suggested that MMPs -positively expressed by PAS reactions-account for the spacing of the fibrous stroma, allowing for reshaping the three dimensional structure of the connective tissue. Myxoid structures are certainly promoting recurrence either via excessive secretion of hyaluronic acids or unknown mechanisms. The undisputed fact is the presence of myxoid structures in all our reported recurrent cases. Both inflammatory cascade and endothelial proliferation have no vital role in the recurrence according to our morphometric results. Finally, PAS stain should give more details in examining PGs than the other recruited counterparts.