Use of the silver phosphate nanoparticles (SPNPs) for their antimicrobial effect on bacterial strains (original) (raw)
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Nanolayered Metal Phosphates as Biocompatible Reservoirs for Antimicrobial Silver Nanoparticles
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This study aimed to synthesize and characterize materials containing silver nanoparticles (AgNP) with polyphosphates (sodium trimetaphosphate (TMP) or sodium hexametaphosphate (HMP), and evaluate their effect against Candida albicans and Streptococcus mutans. The minimum inhibitory concentration (MIC) was determined, which was followed by the quantification of the biofilm by counting colony-forming units (CFUs), the amount of metabolic activity, and the total biomass. The MICs revealed greater effectiveness of composites containing 10% Ag (TMP + Ag10% (T10) and HMP + Ag10% (H10)) against both microorganisms. It was observed that T10 and H10 reduced the formation of biofilms by 56-76% for C. albicans and by 52-94% for S. mutans for total biomass and metabolic activity. These composites promoted significant log reductions in the number of CFUs, between 0.45-1.43 logfor C. albicans and 2.88-3.71 logfor S. mutans (p < .001). These composites demonstrated significant antimicrobial act...
Silver Nanoparticle and their Antimicrobial Properties
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Silver nanoparticles possess broad spectrum antimicrobial properties with evident applicability in biomedical and industrial endeavors. They can be fabricated and modified appropriately in the desirable manner to utilize at their maximum potential. The most noticeable nanoparticle for medical intervention are silver nanoparticles which are renowned for their high antimicrobial activity. Silver ion has been acknowledged as a metal ion that demonstrate anti-mold and anti-algal properties for long time. In the present review, we report antimicrobial properties of silver nanoparticles characterized by several biophysical techniques and their mechanism through generation of reactive oxygen species (ROS).
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Synthesis and applications of silver nanoparticles on bacterial pathogens activity
This research focused on the study effect silver nanoparticles (AgNPs) on bacterial activity. Silver nanoparticle concentrationsare (8, 6) mM. The results showed that the best method to prepare the silver nanoparticles was sunlight method. It concluded that concentration of 8 mM better than 6 mM for processing bacterial activity.The silvernanoparticles are succeeded to inhibit the growth of pathogenic bacteria examined in this study.
Research Journal of Applied Biotechnology, 2019
Silver nanoparticles play a vital role in the development of new antimicrobial substances against a number of pathogenic microorganisms. These nanoparticles due to their smaller size could be very effective as they can improve the antibacterial activity through lysis of bacterial cell wall. The biosynthesis of nanoparticles as an emerging highlight of the intersection of nanotechnology and biotechnology has received increasing attention due to a growing need to develop environmentally benign technologies in material synthesis (Kalishwaralal et al., 2008). In the present investigation, synthesis of silver nanoparticles (AgNPs) was attempted using the isolated pharmaceutical contaminants. The synthesized AgNPs were evaluated for their antibacterial activity against common pharmaceutical contaminants. When AgNPs were mixed with hydrogen peroxide disinfectant they displayed strong synergistic antibacterial. The overall results highlighted the potential use of commonly isolated microorganisms from pharmaceutical industrial areas in the synthesis of AgNPs and their utilization in various applications particularly as antibacterial substance in disinfection and preservation to protect against various biomedical, pharmaceutical based activities.
Synthesis, Characterization and Antimicrobial Activity of Silver Nanoparticles
New Technologies, Development and Application II, 2019
During the past few years, metal nanoparticles received attention due to their interesting optical and electrical properties. Among them, silver nanoparticles (AgNP) showed various specific properties. In this paper, we’ve synthesised silver nanoparticles and tested their antimicrobial activity. As a precursor for silver, we used silver salt-AgNO3. As a stabilizer and also a reducing agent, we used gallic acid monohydrate, because it is known that in strong alkaline solutions, this acid is capable of reducing silver ammonium complex, thus generating stable AgNPs. The characterization was done with UV/VIS spectrophotometer by assessment of absorption maximum λmax in certain interval of time. In order to determine the inhibitory effects of silver nanoparticles, the test diffusion antibiogram method was used. Based on the obtained results, we concluded that nanoparticles synthesized in this way, show excellent antimicrobial activity and can be used as antimicrobial agent.