Leptospirosis: Time to move to molecular epidemiology (original) (raw)

2014, Infection, Genetics and Evolution

AI-generated Abstract

Leptospirosis epidemiology has traditionally relied on serological techniques for the identification of various strains. Recent advancements in molecular methods, particularly DNA sequence polymorphism analysis and real-time PCR, have transformed the diagnosis and understanding of the disease. With the rapid shift to these molecular tools, there's a pressing need to reconcile historical serological data with modern findings, which is crucial for linking animal reservoirs to human infections and enhancing control strategies.