Leptospirosis: Time to move to molecular epidemiology (original) (raw)

Leptospirosis epidemiology has traditionally relied on serological techniques for the identification of various strains. Recent advancements in molecular methods, particularly DNA sequence polymorphism analysis and real-time PCR, have transformed the diagnosis and understanding of the disease. With the rapid shift to these molecular tools, there's a pressing need to reconcile historical serological data with modern findings, which is crucial for linking animal reservoirs to human infections and enhancing control strategies.